octr-1

Caenorhabditis elegans

Enables octopamine receptor activity. Involved in negative regulation of innate immune response; octopamine signaling pathway; and regulation of IRE1-mediated unfolded protein response. Predicted to be located in dendrite. Expressed in head neurons; sensory neurons; tail; uterine toroidal epithelial cell; and in male. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); attention deficit hyperactivity disorder; and type 2 diabetes mellitus. Is an ortholog of human ADRA2A (adrenoceptor alpha 2A).