nep-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Expressed in RIH and pharynx. Human ortholog(s) of this gene implicated in Alzheimer's disease; artery disease (multiple); congestive heart failure; and dilated cardiomyopathy. Is an ortholog of human ECE1 (endothelin converting enzyme 1).