ets-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of axon extension involved in regeneration and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including P1; germ line; head; socket cell; and sperm. Human ortholog(s) of this gene implicated in ovarian cancer. Is an ortholog of human SPDEF (SAM pointed domain containing ETS transcription factor).