hsp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables ATP hydrolysis activity. Involved in determination of adult lifespan; response to heat; and retrograde transport, endosome to Golgi. Located in cytosol and nucleus. Expressed in germ line and intestine. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); brain disease (multiple); and eye disease (multiple). Is an ortholog of human HSPA8 (heat shock protein family A (Hsp70) member 8).