nurf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and methylated histone binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of NURF complex. Expressed in several structures, including head; pharyngeal-intestinal valve; pharynx; tail; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease and amyotrophic lateral sclerosis. Is an ortholog of human BPTF (bromodomain PHD finger transcription factor).