ima-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription factor binding activity; nuclear import signal receptor activity; and nuclear localization sequence binding activity. Involved in several processes, including NLS-bearing protein import into nucleus; cellular component organization; and nematode larval development. Located in cytoplasm and nuclear envelope. Part of nuclear pore. Expressed in germ line; gonad; hypodermis; muscle cell; and neurons. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 88. Is an ortholog of human KPNA3 (karyopherin subunit alpha 3) and KPNA4 (karyopherin subunit alpha 4).