pole-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA binding activity; DNA-directed DNA polymerase activity; and single-stranded DNA 3'-5' DNA exonuclease activity. Predicted to be involved in DNA metabolic process and mitotic cell cycle. Predicted to be located in nucleus. Predicted to be part of epsilon DNA polymerase complex. Human ortholog(s) of this gene implicated in ascending colon cancer; carcinoma (multiple); and mismatch repair cancer syndrome. Is an ortholog of human POLE (DNA polymerase epsilon, catalytic subunit).