fer-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable calcium-dependent phospholipid binding activity. Involved in several processes, including amoeboid sperm motility; membrane organization; and pseudopodium organization. Located in neuronal cell body membrane; organelle membrane; and pseudopodium membrane. Expressed in body wall muscle cell; spermatid; spermatocyte; and in male. Used to study limb-girdle muscular dystrophy. Human ortholog(s) of this gene implicated in Miyoshi muscular dystrophy 1; autosomal recessive limb-girdle muscular dystrophy type 2B; autosomal recessive nonsyndromic deafness 9; distal muscular dystrophy with anterior tibial onset; and hereditary angioedema. Is an ortholog of human DYSF (dysferlin) and MYOF (myoferlin).