• ubh-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables deNEDDylase activity and deubiquitinase activity. Involved in negative regulation of dauer larval development and positive regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in cytoplasm. Expressed in amphid neurons and intestinal cell. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and hereditary spastic paraplegia 79. Is an ortholog of human UCHL1 (ubiquitin C-terminal hydrolase L1) and UCHL3 (ubiquitin C-terminal hydrolase L3).