dpy-22 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transcription coactivator activity. Involved in negative regulation of epidermal growth factor receptor signaling pathway and negative regulation of vulval development. Located in nucleus. Expressed in several structures, including hypodermal cell; intestine; pharynx; and vulva. Human ortholog(s) of this gene implicated in several diseases, including X-linked recessive disease (multiple); major depressive disorder; and phobic disorder. Is an ortholog of human MED12L (mediator complex subunit 12L).