pat-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables transmembrane signaling receptor activity. Involved in several processes, including muscle cell cellular homeostasis; positive regulation of cellular component organization; and regulation of locomotion. Located in M band; cell surface; and striated muscle dense body. Expressed in body wall musculature; distal tip cell; hypodermis; and touch receptor neurons. Human ortholog(s) of this gene implicated in several diseases, including abdominal aortic aneurysm; blood platelet disease (multiple); and von Willebrand's disease (multiple). Is an ortholog of several human genes including ITGA2B (integrin subunit alpha 2b); ITGA5 (integrin subunit alpha 5); and ITGAV (integrin subunit alpha V).