mrp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in dauer larval development; regulatory ncRNA-mediated post-transcriptional gene silencing; and stress response to metal ion. Located in plasma membrane. Expressed in several structures, including intestine; pharyngeal-intestinal valve; pharynx; rectal valve cell; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including bile duct disease (multiple); leukemia (multiple); and lung disease (multiple). Is an ortholog of human ABCC3 (ATP binding cassette subfamily C member 3).