Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; bHLH transcription factor binding activity; and protein dimerization activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including generation of neurons; regulation of metabolic process; and sex differentiation. Located in cytoplasm and nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including distal tip cell; enteric muscle; lateral ganglion; ray precursor cell; and terminal bulb. Used to study obesity. Human ortholog(s) of this gene implicated in several diseases, including Fuchs' endothelial dystrophy; Pitt-Hopkins syndrome; and agammaglobulinemia (multiple). Is an ortholog of human TCF12 (transcription factor 12); TCF3 (transcription factor 3); and TCF4 (transcription factor 4).
Predicted to enable protein dimerization activity. Is an ortholog of C. elegans hlh-2. In C. elegans, hlh-2 is involved in several processes, including generation of neurons; regulation of metabolic process; and sex differentiation.
Predicted to enable protein dimerization activity. Is an ortholog of C. elegans hlh-2. In C. elegans, hlh-2 is involved in several processes, including generation of neurons; regulation of metabolic process; and sex differentiation.
Predicted to enable protein dimerization activity. Is an ortholog of C. elegans hlh-2. In C. elegans, hlh-2 is involved in several processes, including generation of neurons; regulation of metabolic process; and sex differentiation.
Predicted to enable protein dimerization activity. Is an ortholog of C. elegans hlh-2. In C. elegans, hlh-2 is involved in several processes, including generation of neurons; regulation of metabolic process; and sex differentiation.
Is an ortholog of C. elegans hlh-2. In C. elegans, hlh-2 is involved in several processes, including generation of neurons; regulation of metabolic process; and sex differentiation.
Predicted to enable protein dimerization activity. Is an ortholog of C. elegans hlh-2. In C. elegans, hlh-2 is involved in several processes, including generation of neurons; regulation of metabolic process; and sex differentiation.
Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; egl-9; and hlh-2 based on RNA-seq and microarray studies.
Predicted to enable protein dimerization activity. Is an ortholog of C. elegans hlh-2. In C. elegans, hlh-2 is involved in several processes, including generation of neurons; regulation of metabolic process; and sex differentiation.