pax-1

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to Gram-negative bacterium. Located in nucleus. Expressed in epithelial cell and pharyngeal cell. Human ortholog(s) of this gene implicated in branchiootorenal syndrome and tooth agenesis. Is an ortholog of human PAX9 (paired box 9).