acr-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in calcium ion import across plasma membrane. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in several diseases, including congenital myasthenic syndrome (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human CHRNA1 (cholinergic receptor nicotinic alpha 1 subunit) and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit).