- rba-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable histone binding activity. Involved in cell fate specification; nematode male tail tip morphogenesis; and regulation of neurogenesis. Predicted to be located in nucleus. Predicted to be part of ESC/E(Z) complex and NuRD complex. Is an ortholog of human RBBP7 (RB binding protein 7, chromatin remodeling factor).
- lin-35 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of cell cycle; negative regulation of vulval development; and positive regulation of brood size. Located in nucleus. Expressed in several structures, including head and tail. Used to study intellectual disability. Human ortholog(s) of this gene implicated in several diseases, including germ cell cancer (multiple); high grade glioma (multiple); and urinary system cancer (multiple). Is an ortholog of human RBL1 (RB transcriptional corepressor like 1) and RBL2 (RB transcriptional corepressor like 2).
- rbpl-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Expressed in intestine; neurons; spermatheca; and vulva. Is an ortholog of human RBBP6 (RB binding protein 6, ubiquitin ligase).
- Nom1 [Search on AGR]
Homo sapiens Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 [PubMed 15715967]).[supplied by OMIM, Mar 2008]
- YLR419W [Search on AGR]
Saccharomyces cerevisiae Putative helicase with limited sequence similarity to human Rb protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR419W is not an essential gene