cpl-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable cysteine-type endopeptidase activity. Involved in several processes, including lipid droplet disassembly; positive regulation of vitellogenesis; and regulation of apoptosis involved in tissue homeostasis. Located in several cellular components, including lysosome; vesicle lumen; and yolk granule. Expressed in several structures, including cuticle; eggshell; hermaphrodite gonad; pharynx; and vulva. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy and type 2 diabetes mellitus. Is an ortholog of human CTSL (cathepsin L).