uba-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables UFM1 activating enzyme activity and ubiquitin conjugating enzyme binding activity. Involved in determination of adult lifespan; reproduction; and stress response to metal ion. Predicted to be located in cytosol. Used to study early infantile epileptic encephalopathy. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 24 and developmental and epileptic encephalopathy 44. Is an ortholog of human UBA5 (ubiquitin like modifier activating enzyme 5).