• nep-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable metalloendopeptidase activity. Involved in olfactory learning and regulation of chemotaxis. Located in cell surface. Expressed in GLR and body wall musculature. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Charcot-Marie-Tooth disease axonal type 2T; X-linked dominant hypophosphatemic rickets; and cerebellar ataxia type 43. Is an ortholog of human MME (membrane metalloendopeptidase) and MMEL1 (membrane metalloendopeptidase like 1).