---
count: 1
page: all
query: T12D8.6
results:
-
allele:
-
class: variation
id: WBVar01499774
label: gk963887
-
class: variation
id: WBVar00876758
label: gk840088
-
class: variation
id: WBVar00414076
label: gk190833
-
class: variation
id: WBVar00414072
label: gk190829
-
class: variation
id: WBVar00414077
label: gk190834
-
class: variation
id: WBVar00414073
label: gk190830
-
class: variation
id: WBVar00876757
label: gk570450
-
class: variation
id: WBVar01498679
label: gk963904
-
class: variation
id: WBVar00876760
label: gk496570
-
class: variation
id: WBVar00414074
label: gk190831
-
class: variation
id: WBVar01498619
label: gk963552
-
class: variation
id: WBVar00876752
label: gk490171
-
class: variation
id: WBVar00876754
label: gk340067
-
class: variation
id: WBVar00876756
label: gk679110
-
class: variation
id: WBVar00876759
label: gk655316
-
class: variation
id: WBVar00876753
label: gk598456
-
class: variation
id: WBVar00876761
label: gk538873
-
class: variation
id: WBVar00876755
label: gk558849
-
class: variation
id: WBVar01499629
label: gk963715
-
class: variation
id: WBVar00414075
label: gk190832
dead: !!perl/scalar:JSON::PP::Boolean 0
description: Predicted to enable calcium ion binding activity. Involved in mitotic cytokinesis. Located in actin cytoskeleton. Human ortholog(s) of this gene implicated in congenital myopathy 14; familial atrial fibrillation; and hypertrophic cardiomyopathy 8. Is an ortholog of human MYL4 (myosin light chain 4); MYL6 (myosin light chain 6); and MYL6B (myosin light chain 6B).
label: mlc-5
legacy_description: mlc-5 encodes a protein containing two EF-hand domains that is the C. elegans myosin II essential light chain ortholog; MLC-5 activity is required for cytokinesis and for epithelial morphogenesis during embryonic elongation; a GFP::MLC-5 fusion protein is expressed during embryogenesis in the lateral hypodermal seam cells as well as in the dorsal and ventral hypodermal cells where it exhibits co-localization with actin bundles; MLC-5 subcellular localization depends upon activity of MLC-4, a myosin regulatory light chain; in turn, MLC-5 activity is required for proper localization of MLC-4 and the non-muscle myosin II NMY-2.
merged_into: ~
name:
class: gene
highlight:
other_names:
- T12D8.6
- T12D8.6
id: WBGene00011734
label: mlc-5
other_names:
- T12D8.6
- CELE_T12D8.6
- CE16403
- T12D8.6.1
- T12D8.6
taxonomy: c_elegans
other_names:
- T12D8.6
- CELE_T12D8.6
- CE16403
- T12D8.6.1
- T12D8.6
page_type: gene
species:
key: c_elegans
name: Caenorhabditis elegans
taxonomy:
genus: Caenorhabditis
id: c_elegans
species: elegans
wbid: WBGene00011734
species: ~
type: gene
uri: search/gene/T12D8.6/all