Is affected by several genes including daf-2; rsks-1; and hpl-2 based on tiling array and microarray studies. Is affected by mianserin and indole based on RNA-seq and microarray studies.
Predicted to enable protein serine/threonine kinase activity. Involved in determination of adult lifespan; nematode larval development; and positive regulation of metabolic process. Predicted to be located in cytoplasm and nucleoplasm. Expressed in several structures, including Eala; Ealaa; Ealp; Earaa; and Earp. Is an ortholog of human RPS6KB2 (ribosomal protein S6 kinase B2).
Predicted to enable alpha-tubulin binding activity and gamma-tubulin binding activity. Involved in cytoplasmic sequestering of protein and determination of adult lifespan. Predicted to be located in early endosome and recycling endosome. Predicted to be part of WASH complex. Expressed in neurons. Is an ortholog of human WASH2P (WASP family homolog 2, pseudogene) and WASHC1 (WASH complex subunit 1).
Enables heme binding activity; iron ion binding activity; and oxygen binding activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in neurons and somatic nervous system.