- grd-11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in protein autoprocessing. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including bone disease (multiple); gastrointestinal system cancer (multiple); and glomerulonephritis (multiple). Is an ortholog of human DHH (desert hedgehog signaling molecule); IHH (Indian hedgehog signaling molecule); and SHH (sonic hedgehog signaling molecule).
- Arr2 [Search on AGR]
Saccharomyces cerevisiae Arsenate reductase required for arsenate resistance; converts arsenate to arsenite which can then be exported from cells by Arr3p
- Rgsc1453 [Search on AGR]
Mus musculus PHENOTYPE: Mice homozygous for a mutation of this gene have curly hair coats, then later develop alopecia. [provided by MGI curators]
- nrde-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables siRNA binding activity. Involved in RNA import into nucleus; olfactory learning; and regulation of gene expression. Located in nucleus. Part of RNAi effector complex. Expressed in several structures, including AWC; gonad; hypodermis; pharynx; and vulva.
- DPP1 [Search on AGR]
Saccharomyces cerevisiae Diacylglycerol pyrophosphate (DGPP) phosphatase; zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism
- Uba4 [Search on AGR]
Saccharomyces cerevisiae E1-like protein that activates Urm1p before urmylation; also acts in thiolation of the wobble base of cytoplasmic tRNAs by adenylating and then thiolating Urm1p; receives sulfur from Tum1p
- Msh6 [Search on AGR]
Drosophila melanogaster Msh6 (Msh6) encodes a heterodimer with the product of spel1 to detect base-base mismatches and small insertion/deletion loops. It then recruits the rest of the mismatch repair machinery.