- uvs-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA polymerase II complex binding activity. Involved in response to UV and transcription-coupled nucleotide-excision repair. Predicted to be located in chromosome. Human ortholog(s) of this gene implicated in UV-sensitive syndrome. Is an ortholog of human UVSSA (UV stimulated scaffold protein A).
- xpa-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable damaged DNA binding activity. Involved in several processes, including DNA repair; determination of adult lifespan; and response to UV-C. Located in nucleus. Human ortholog(s) of this gene implicated in xeroderma pigmentosum group A. Is an ortholog of human XPA (XPA, DNA damage recognition and repair factor).
- ercc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables enzyme binding activity and identical protein binding activity. Involved in UV-damage excision repair and base-excision repair. Predicted to be located in nucleus. Predicted to be part of ERCC4-ERCC1 complex and nucleotide-excision repair factor 1 complex. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and hematologic cancer (multiple). Is an ortholog of human ERCC1 (ERCC excision repair 1, endonuclease non-catalytic subunit).
- T23G11.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable SNARE binding activity. Predicted to be involved in SNARE complex assembly. Predicted to be located in endosome and lytic vacuole. Is an ortholog of human UVRAG (UV radiation resistance associated).
- Y34B4A.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable SNARE binding activity. Predicted to be involved in SNARE complex assembly. Predicted to be located in endosome and lytic vacuole. Is an ortholog of human UVRAG (UV radiation resistance associated).
- xpg-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 5'-flap endonuclease activity. Predicted to be involved in double-strand break repair via homologous recombination. Human ortholog(s) of this gene implicated in several diseases, including cerebrooculofacioskeletal syndrome 3; respiratory system cancer (multiple); and xeroderma pigmentosum group G. Is an ortholog of human ERCC5 (ERCC excision repair 5, endonuclease).
- csb-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP-dependent activity, acting on DNA and DNA binding activity. Involved in UV protection and transcription-coupled nucleotide-excision repair. Predicted to be located in nucleus. Expressed in several structures, including copulatory spicule; egg-laying apparatus; neurons; oocyte; and postcloacal sensillum. Used to study Cockayne syndrome. Human ortholog(s) of this gene implicated in several diseases, including Cockayne syndrome (multiple); gastrointestinal system cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human ERCC6 (ERCC excision repair 6, chromatin remodeling factor).