- pfd-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein folding chaperone. Predicted to be involved in protein folding. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Is an ortholog of human PFDN2 (prefoldin subunit 2).
- sid-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in RNA transport and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in apical plasma membrane and cytoplasm. Expressed in ciliated neurons; excretory duct; intestine; and in male.
- mut-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable nucleotidyltransferase activity. Involved in several processes, including embryo development; meiotic chromosome segregation; and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in mutator focus. Expressed in germ line.
- rrf-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA-dependent RNA polymerase activity. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be part of nuclear RNA-directed RNA polymerase complex.
- cls-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable microtubule binding activity. Involved in cytoplasmic streaming; mitotic cytokinesis; and organelle organization. Located in several cellular components, including kinetochore; microtubule cytoskeleton; and nucleus. Expressed in embryonic cell. Is an ortholog of human CLASP2 (cytoplasmic linker associated protein 2).
- vha-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in programmed cell death and proton transmembrane transport. Predicted to be located in membrane. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Expressed in excretory cell and rectum. Human ortholog(s) of this gene implicated in thyroid gland carcinoma. Is an ortholog of human ATP6V0C (ATPase H+ transporting V0 subunit c).
- nud-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable microtubule binding activity. Involved in GABAergic synaptic transmission; nuclear migration; and synaptic vesicle transport. Located in nuclear envelope. Expressed in several structures, including germ cell; hypodermal cell; non-striated muscle; rectal valve cell; and tail hypodermis. Used to study epilepsy and lissencephaly. Human ortholog(s) of this gene implicated in lissencephaly 4 and schizophrenia. Is an ortholog of human NDE1 (nudE neurodevelopment protein 1) and NDEL1 (nudE neurodevelopment protein 1 like 1).
- rnp-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable U1 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U1 snRNP. Human ortholog(s) of this gene implicated in Alzheimer's disease; connective tissue disease; and disease of cellular proliferation. Is an ortholog of human SNRPA (small nuclear ribonucleoprotein polypeptide A) and SNRPB2 (small nuclear ribonucleoprotein polypeptide B2).