- F36G3.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable zinc ion binding activity. Predicted to be located in lysosomal membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1C. Is an ortholog of human LITAF (lipopolysaccharide induced TNF factor).
- exos-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in RNA metabolic process. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1C. Is an ortholog of human EXOSC8 (exosome component 8).
- num-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables enzyme binding activity and protein domain specific binding activity. Involved in endocytic recycling; phospholipid transport; and protein targeting to membrane. Located in basolateral plasma membrane and cytoplasm. Expressed in several structures, including alimentary muscle; hermaphrodite gonad; nerve ring; pseudocoelom; and rectal valve cell. Is an ortholog of human NUMB (NUMB endocytic adaptor protein) and NUMBL (NUMB like endocytic adaptor protein).
- rme-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable phosphatidylinositol phosphate binding activity. Involved in endocytic recycling. Located in clathrin-coated pit. Expressed in several structures, including engulfing cell and linker cell. Is an ortholog of human DENND1A (DENN domain containing 1A); DENND1B (DENN domain containing 1B); and DENND1C (DENN domain containing 1C).
- ZC328.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable sterol binding activity and sterol transfer activity. Predicted to be involved in intracellular sterol transport. Predicted to be located in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. Expressed in head. Is an ortholog of human GRAMD1C (GRAM domain containing 1C).
- sptl-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable serine C-palmitoyltransferase activity. Predicted to be involved in ceramide biosynthetic process and sphingosine biosynthetic process. Predicted to be part of serine C-palmitoyltransferase complex. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 1C. Is an ortholog of human SPTLC2 (serine palmitoyltransferase long chain base subunit 2) and SPTLC3 (serine palmitoyltransferase long chain base subunit 3).
- Cimap1c [Search on AGR]
Rattus norvegicus Orthologous to human CIMAP1C (ciliary microtubule associated protein 1C); INTERACTS WITH amitrole; bisphenol A; clotrimazole.
- sptl-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable serine C-palmitoyltransferase activity. Predicted to be involved in ceramide biosynthetic process and sphingosine biosynthetic process. Predicted to be part of serine C-palmitoyltransferase complex. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 1C. Is an ortholog of human SPTLC2 (serine palmitoyltransferase long chain base subunit 2) and SPTLC3 (serine palmitoyltransferase long chain base subunit 3).
- Tmed8 [Search on AGR]
Homo sapiens ASSOCIATED WITH genetic disease; hereditary sensory and autonomic neuropathy type 1C; INTERACTS WITH 17beta-estradiol; afimoxifene; aflatoxin B1