Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human RNF19A (ring finger protein 19A, RBR E3 ubiquitin protein ligase).
Predicted to enable clathrin binding activity. Involved in receptor-mediated endocytosis. Predicted to be located in cytoplasm; intracellular membrane-bounded organelle; and vesicle. Human ortholog(s) of this gene implicated in Parkinson's disease 19A. Is an ortholog of human DNAJC6 (DnaJ heat shock protein family (Hsp40) member C6).
Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of ubiquitin ligase complex. Expressed in tail. Is an ortholog of human RNF19A (ring finger protein 19A, RBR E3 ubiquitin protein ligase) and RNF19B (ring finger protein 19B).
Is affected by several genes including eat-2; prg-1; and alg-1 based on RNA-seq studies. Is affected by nicotine and sanguinarine based on RNA-seq studies.
Predicted to enable ATP binding activity and hydrolase activity. Involved in positive regulation of apoptotic process and response to zinc ion. Orthologous to human DDX19A (DEAD-box helicase 19A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; diazinon.
Predicted to enable RNA binding activity and RNA helicase activity. Involved in germ cell development. Located in P granule. Expressed in tail. Is an ortholog of human DDX19A (DEAD-box helicase 19A) and DDX19B (DEAD-box helicase 19B).
Predicted to enable zinc ion binding activity. Predicted to be involved in regulation of protein catabolic process at postsynapse, modulating synaptic transmission. Predicted to be located in postsynapse. Predicted to be active in glutamatergic synapse and hippocampal mossy fiber to CA3 synapse. Orthologous to human RNF19A (ring finger protein 19A, RBR E3 ubiquitin protein ligase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including positive regulation of nitrogen compound metabolic process; regulation of cellular response to transforming growth factor beta stimulus; and regulation of signal transduction. Predicted to act upstream of or within several processes, including long-term synaptic potentiation; pre-B cell differentiation; and ventricular septum morphogenesis. Orthologous to human MIR19A (microRNA 19a); INTERACTS WITH 2-methoxyethanol; aflatoxin B1; atrazine.