Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in recycling endosome. Is an ortholog of human DENND6A (DENN domain containing 6A) and DENND6B (DENN domain containing 6B).
Predicted to enable transferase activity and zinc ion binding activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 6A. Is an ortholog of human PEX10 (peroxisomal biogenesis factor 10).
Enables phosphatase binding activity. Involved in several processes, including nematode larval development; phosphatidylinositol metabolic process; and pinocytosis. Located in apical plasma membrane and cytosol. Expressed in several structures, including anal depressor muscle; coelomocyte; intestinal cell; preanal ganglion; and tail. Used to study centronuclear myopathy. Is an ortholog of human MTMR6 (myotubularin related protein 6); MTMR7 (myotubularin related protein 7); and MTMR8 (myotubularin related protein 8).
Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Involved in nematode male tail mating organ morphogenesis. Predicted to be located in membrane. Expressed in several structures, including hook; inner labial neurons; pharyngeal cell; ray; and vulval cell. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy. Is an ortholog of several human genes including SEMA6A (semaphorin 6A); SEMA6B (semaphorin 6B); and SEMA6C (semaphorin 6C).
Predicted to enable cysteine-type deubiquitinase activity. Orthologous to human OTUD6A (OTU deubiquitinase 6A); INTERACTS WITH Cuprizon; benzo[a]pyrene (ortholog); bisphenol A (ortholog).
Predicted to be located in endoplasmic reticulum. Orthologous to human TRAPPC6A (trafficking protein particle complex subunit 6A); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Is an ortholog of C. elegans cox-6A.
Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Is an ortholog of C. elegans cox-6A.