- atg-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in regulation of presynapse assembly. Located in cytoplasm and presynapse. Expressed in several structures, including AIY; hypodermis; nerve ring; neuronal sheath cell; and spermatheca. Is an ortholog of human ATG9A (autophagy related 9A).
- T10E9.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable mRNA binding activity. Predicted to be located in cytoplasm and nucleus. Predicted to be part of polysome. Human ortholog(s) of this gene implicated in congenital myopathy 9A and congenital myopathy 9B. Is an ortholog of human FXR1 (FMR1 autosomal homolog 1).
- Or9a [Search on AGR]
Drosophila melanogaster Odorant receptor 9a (Or9a) encodes a multi-transmembrane chemoreceptor that mediates response to volatile chemicals.
- Nhe2 [Search on AGR]
Drosophila melanogaster Na[+]/H[+] hydrogen exchanger 2 (Nhe2) encodes a Na-H exchanger of the SLC family 9A that increases intracellular pH. The product of Nhe2 activity promotes proliferation, morphogenesis and planar cell polarity, and contributes to oncogene-induced metastatic cell behaviors.
- Atg9a [Search on AGR]
Rattus norvegicus Predicted to enable phospholipid scramblase activity. Involved in response to nutrient levels. Located in late endosome. Is active in synaptic vesicle. Orthologous to human ATG9A (autophagy related 9A); PARTICIPATES IN autophagy pathway; INTERACTS WITH (+)-schisandrin B; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
- Clec9a [Search on AGR]
Rattus norvegicus Predicted to enable carbohydrate binding activity. Predicted to be involved in positive regulation of cytokine production and receptor-mediated endocytosis. Predicted to be located in cell surface. Orthologous to human CLEC9A (C-type lectin domain containing 9A); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; amphetamine.
- Atp9a [Search on AGR]
Rattus norvegicus Predicted to enable protease binding activity. Predicted to be involved in neuron projection morphogenesis and regulation of vesicle-mediated transport. Predicted to be located in several cellular components, including endosome; perinuclear region of cytoplasm; and trans-Golgi network membrane. Orthologous to human ATP9A (ATPase phospholipid transporting 9A (putative)); INTERACTS WITH ammonium chloride; atrazine; benzene.
- Pde9a [Search on AGR]
Rattus norvegicus Predicted to enable 3',5'-cyclic-GMP phosphodiesterase activity and identical protein binding activity. Involved in negative regulation of neural precursor cell proliferation and positive regulation of long-term synaptic potentiation. Located in perikaryon. Used to study Huntington's disease and congestive heart failure. Orthologous to human PDE9A (phosphodiesterase 9A); PARTICIPATES IN purine metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
- nab-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable actin filament binding activity. Involved in synapse assembly. Located in actin cytoskeleton and presynapse. Expressed in several structures, including egg-laying apparatus; excretory canal; hermaphrodite distal tip cell; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; hepatocellular carcinoma; and schizophrenia. Is an ortholog of human PPP1R9A (protein phosphatase 1 regulatory subunit 9A) and PPP1R9B (protein phosphatase 1 regulatory subunit 9B).
- Wnt9a [Search on AGR]
Rattus norvegicus Predicted to enable receptor ligand activity. Predicted to be involved in negative regulation of cell population proliferation. Predicted to act upstream of or within several processes, including embryonic morphogenesis; negative regulation of chondrocyte differentiation; and positive regulation of smoothened signaling pathway. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human WNT9A (Wnt family member 9A); PARTICIPATES IN altered Wnt signaling, canonical pathway; pancreatic cancer pathway; Wnt signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.