- vab-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable actin filament binding activity and structural molecule activity. Involved in epidermis morphogenesis. Located in apical plasma membrane; basal plasma membrane; and hemidesmosome. Expressed in several structures, including gonad; intestinal lumen; nerve ring; pharynx; and vulval cell. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex; hereditary sensory and autonomic neuropathy type 6; and lissencephaly 9 with complex brainstem malformation. Is an ortholog of human DST (dystonin).
- trmt-10A [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable tRNA (guanine-N1-)-methyltransferase activity and tRNA binding activity. Predicted to be involved in tRNA N1-guanine methylation. Predicted to be located in nucleoplasm. Is an ortholog of human TRMT10A (tRNA methyltransferase 10A).
- pde-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 3',5'-cyclic-GMP phosphodiesterase activity and cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Involved in several processes, including determination of adult lifespan; negative regulation of cGMP-mediated signaling; and response to alkaline pH. Expressed in AFDL and AFDR. Is an ortholog of human PDE10A (phosphodiesterase 10A).
- Or10a [Search on AGR]
Drosophila melanogaster Odorant receptor 10a (Or10a) encodes a multi-transmembrane chemoreceptor that mediates response to volatile chemicals.
- prx-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in protein import into peroxisome membrane. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 10A. Is an ortholog of human PEX3 (peroxisomal biogenesis factor 3).
- Ccdc138 [Search on AGR]
Homo sapiens ASSOCIATED WITH distal hereditary motor neuronopathy type 7A; ectodermal dysplasia 10A; ectodermal dysplasia 10B; INTERACTS WITH (+)-catechin; (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine
- Wfdc10a [Search on AGR]
Rattus norvegicus Orthologous to several human genes including WFDC10A (WAP four-disulfide core domain 10A); INTERACTS WITH 6-propyl-2-thiouracil; all-trans-retinoic acid; bisphenol A.
- Myo10A [Search on AGR]
Drosophila melanogaster Myosin 10A (Myo10A) encodes an unconventional myosin of the MyTH-FERM superclass that traffics sensory, cytoskeletal, and adhesion cargos. It is required during dorsal closure for proper epithelial alignment and for zippering and fusion of the two epithelial sheets.
- spp-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in sphingolipid metabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in several diseases, including cystic fibrosis; lung disease (multiple); and sphingolipidosis (multiple). Is an ortholog of human PSAP (prosaposin) and PSAPL1 (prosaposin like 1).