- lev-11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables actin filament binding activity. Involved in several processes, including actin filament organization; regulation of actin polymerization or depolymerization; and spicule insertion. Located in striated muscle thin filament. Expressed in several structures, including body wall musculature; germ line; intestine; non-striated muscle; and pharynx. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); muscle tissue disease (multiple); and thyroid gland papillary carcinoma. Is an ortholog of several human genes including TPM1 (tropomyosin 1); TPM2 (tropomyosin 2); and TPM3 (tropomyosin 3).
- slc-25A46 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in mitochondrial fission. Predicted to be located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1E. Is an ortholog of human SLC25A46 (solute carrier family 25 member 46).
- Y105E8B.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable beta-glucuronidase activity and carbohydrate binding activity. Predicted to be involved in glucuronoside catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in Sly syndrome. Is an ortholog of human GUSB (glucuronidase beta).