- pfkb-1.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to be located in cytosol. Is an ortholog of several human genes including PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1); PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2); and PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3).
- ift-20 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in centrosome localization; intraciliary transport; and protein localization to cilium. Located in dendrite; neuronal cell body; and non-motile cilium. Expressed in ciliated neurons; sensory neurons; and tail. Is an ortholog of human IFT20 (intraflagellar transport 20).
- F53H1.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in recycling endosome. Is an ortholog of human DENND6A (DENN domain containing 6A) and DENND6B (DENN domain containing 6B).
- trpp-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in cis-Golgi network and trans-Golgi network. Predicted to be part of TRAPP complex. Is an ortholog of human TRAPPC6B (trafficking protein particle complex subunit 6B).
- mlc-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable calcium ion binding activity. Predicted to be part of myosin II complex. Human ortholog(s) of this gene implicated in cardiomyopathy and familial atrial fibrillation. Is an ortholog of human MYL4 (myosin light chain 4); MYL6 (myosin light chain 6); and MYL6B (myosin light chain 6B).
- sec-15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Predicted to be part of exocyst. Expressed in embryonic cell; excretory canal; and hypodermis. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia with joint laxity type 3. Is an ortholog of human EXOC6B (exocyst complex component 6B).
- swsn-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable chromatin binding activity. Predicted to be involved in nervous system development and regulation of transcription by RNA polymerase II. Predicted to be part of NuA4 histone acetyltransferase complex and SWI/SNF complex. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 76. Is an ortholog of human ACTL6B (actin like 6B).
- smp-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Involved in nematode male tail mating organ morphogenesis. Predicted to be located in membrane. Expressed in several structures, including hook; inner labial neurons; pharyngeal cell; ray; and vulval cell. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy. Is an ortholog of several human genes including SEMA6A (semaphorin 6A); SEMA6B (semaphorin 6B); and SEMA6C (semaphorin 6C).
- Y110A7A.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be located in cytoplasm. Expressed in head. Used to study high grade glioma. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder and hypogonadotropic hypogonadism 14 with or without anosmia. Is an ortholog of human WDR11 (WD repeat domain 11).