Enriched in intestine based on tiling array and RNA-seq studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by fourteen chemicals including Ethanol; methylmercuric chloride; and rotenone based on RNA-seq and microarray studies.
Predicted to enable GTPase activity. Predicted to be involved in mitochondrial translation and ribosome disassembly. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 39. Is an ortholog of human GFM2 (GTP dependent ribosome recycling factor mitochondrial 2).
Predicted to enable calmodulin binding activity and syntaxin-1 binding activity. Involved in regulation of multicellular organismal process; spermatogenesis; and synaptic vesicle exocytosis. Located in presynaptic active zone. Expressed in head neurons; neurons; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is an ortholog of human UNC13C (unc-13 homolog C).
Enables BH domain binding activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and positive regulation of apoptotic process.