Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Keshan disease; glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2C19 (cytochrome P450 family 2 subfamily C member 19); and CYP2C8 (cytochrome P450 family 2 subfamily C member 8).
Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of prefoldin complex. Is an ortholog of human PFDN4 (prefoldin subunit 4).
Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Is an ortholog of human DCAF4 (DDB1 and CUL4 associated factor 4); DCAF4L1 (DDB1 and CUL4 associated factor 4 like 1); and DCAF4L2 (DDB1 and CUL4 associated factor 4 like 2).
Involved in determination of adult lifespan and methylglyoxal metabolic process. Expressed widely. Is an ortholog of human GLOD4 (glyoxalase domain containing 4).