hsp-60 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including mitochondrial unfolded protein response; mitochondrion organization; and nematode larval development. Located in mitochondrion. Expressed in hypodermis; intestine; muscle cell; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; artery disease (multiple); and autoimmune disease of musculoskeletal system (multiple). Is an ortholog of human HSPD1 (heat shock protein family D (Hsp60) member 1).