pvf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable growth factor receptor binding activity. Involved in negative regulation of netrin-activated signaling pathway and nematode male tail tip morphogenesis. Predicted to be located in extracellular space. Expressed in body wall musculature. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; central nervous system cancer (multiple); diabetic retinopathy (multiple); and reproductive organ cancer (multiple). Is an ortholog of human PDGFA (platelet derived growth factor subunit A) and PDGFB (platelet derived growth factor subunit B).