Predicted to enable 5S rRNA binding activity. Involved in positive regulation of cellular respiration. Located in nucleolus. Is an ortholog of human NOP53 (NOP53 ribosome biogenesis factor).
Predicted to enable SUMO transferase activity. Predicted to be involved in homologous chromosome pairing at meiosis and protein sumoylation. Predicted to be located in synaptonemal complex. Human ortholog(s) of this gene implicated in spermatogenic failure 62. Is an ortholog of human RNF212 (ring finger protein 212).
Predicted to enable K48-linked deubiquitinase activity and cysteine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human MINDY1 (MINDY lysine 48 deubiquitinase 1) and MINDY2 (MINDY lysine 48 deubiquitinase 2).
Involved in miRNA-mediated gene silencing by inhibition of translation and positive regulation of development, heterochronic. Expressed in P5.p hermaphrodite; P7.p hermaphrodite; RID; and seam cell. Used to study Parkinson's disease.
Predicted to enable SUMO transferase activity. Involved in embryo development; meiotic chromosome segregation; and synaptonemal complex disassembly. Located in synaptonemal complex. Is an ortholog of human RNF212B (ring finger protein 212B).