gly-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables polypeptide N-acetylgalactosaminyltransferase activity. Involved in protein O-linked glycosylation via threonine. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in colorectal cancer. Is an ortholog of human GALNT12 (polypeptide N-acetylgalactosaminyltransferase 12); GALNT4 (polypeptide N-acetylgalactosaminyltransferase 4); and POC1B-GALNT4 (POC1B-GALNT4 readthrough).
Y39E4B.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 7SK snRNA binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleoplasm.
rege-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleus. Expressed in tail. Human ortholog(s) of this gene implicated in hepatitis B. Is an ortholog of human ZC3H12A (zinc finger CCCH-type containing 12A); ZC3H12B (zinc finger CCCH-type containing 12B); and ZC3H12C (zinc finger CCCH-type containing 12C).
prx-19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable peroxisome membrane targeting sequence binding activity. Involved in nematode larval development. Predicted to be located in peroxisomal membrane. Expressed in pharynx. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 12A. Is an ortholog of human PEX19 (peroxisomal biogenesis factor 19).
aqp-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable channel activity. Involved in innate immune response. Predicted to be located in cytoplasm. Is an ortholog of human AQP11 (aquaporin 11); AQP12A (aquaporin 12A); and AQP12B (aquaporin 12B).
aqp-11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable channel activity. Predicted to be involved in transmembrane transport. Predicted to be located in cytoplasm. Is an ortholog of human AQP11 (aquaporin 11); AQP12A (aquaporin 12A); and AQP12B (aquaporin 12B).
Hspa12a [Search on AGR]
Rattus norvegicus Orthologous to human HSPA12A (heat shock protein family A (Hsp70) member 12A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aldehydo-D-glucose.
Aqp12a [Search on AGR]
Rattus norvegicus Predicted to be involved in transmembrane transport. Predicted to be located in cytoplasm. Orthologous to several human genes including AQP12A (aquaporin 12A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.
nuo-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in response to oxidative stress. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease and nuclear type mitochondrial complex I deficiency 33. Is an ortholog of human NDUFA6 (NADH:ubiquinone oxidoreductase subunit A6).
CRE03050 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity and snRNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Is an ortholog of C. elegans Y39E4B.6.
CBG24164 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity and snRNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Is an ortholog of C. elegans Y39E4B.6.
CBN21775 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity and snRNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Is an ortholog of C. elegans Y39E4B.6.
CBN23689 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity and snRNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Is an ortholog of C. elegans Y39E4B.6.
CJA04763 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Predicted to enable cyclin-dependent protein serine/threonine kinase inhibitor activity and snRNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Is an ortholog of C. elegans Y39E4B.6.
Myl12a [Search on AGR]
Rattus norvegicus Predicted to enable GTPase binding activity and glutamate receptor binding activity. Predicted to be involved in platelet aggregation. Predicted to act upstream of or within protein localization to plasma membrane and regulation of cell shape. Part of protein-containing complex. Orthologous to human MYL12A (myosin light chain 12A); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
lgg-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in cellular response to toxic substance; determination of adult lifespan; and xenophagy. Acts upstream of or within with a positive effect on plasma membrane repair. Located in autophagosome membrane. Is an ortholog of human ATG12 (autophagy related 12).
Mvb12a [Search on AGR]
Rattus norvegicus Predicted to enable lipid binding activity and ubiquitin binding activity. Predicted to be involved in regulation of epidermal growth factor receptor signaling pathway. Predicted to be located in several cellular components, including centrosome; cytosol; and vesicle. Predicted to be part of ESCRT I complex. Orthologous to human MVB12A (multivesicular body subunit 12A); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride.
Pex19 [Search on AGR]
Rattus norvegicus Predicted to enable ATPase binding activity; peroxisome membrane class-1 targeting sequence binding activity; and protein carrier chaperone. Predicted to be involved in chaperone-mediated protein folding; peroxisome organization; and protein stabilization. Located in brush border membrane and peroxisome. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 12A. Orthologous to human PEX19 (peroxisomal biogenesis factor 19); INTERACTS WITH (+)-schisandrin B; 2,6-dinitrotoluene; 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole.
Tnfrsf12a [Search on AGR]
Rattus norvegicus Predicted to be involved in positive regulation of extrinsic apoptotic signaling pathway; regulation of angiogenesis; and regulation of wound healing. Predicted to act upstream of or within extrinsic apoptotic signaling pathway; positive regulation of axon extension; and substrate-dependent cell migration, cell attachment to substrate. Predicted to be located in cell surface; plasma membrane; and ruffle. Orthologous to human TNFRSF12A (TNF receptor superfamily member 12A); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate.
Il12a [Search on AGR]
Rattus norvegicus Predicted to enable interleukin-12 beta subunit binding activity; interleukin-27 binding activity; and protein heterodimerization activity. Predicted to contribute to cytokine activity and growth factor activity. Involved in response to granulocyte colony-stimulating factor. Predicted to be located in cell surface and cytoplasm. Predicted to be part of interleukin-12 complex. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in hepatitis C; hepatocellular carcinoma; and primary biliary cholangitis. Orthologous to human IL12A (interleukin 12A); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-27 signaling pathway; allograft rejection pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 2,2',4,4'-Tetrabromodiphenyl ether; ammonium chloride.
Ppp1r12a [Search on AGR]
Rattus norvegicus Enables phosphoprotein phosphatase activity. Predicted to be involved in several processes, including centrosome cycle; mitotic cell cycle; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular response to xenobiotic stimulus and regulation of nucleocytoplasmic transport. Predicted to be located in several cellular components, including cytoskeleton; kinetochore; and sarcomere. Predicted to be part of PTW/PP1 phosphatase complex. Orthologous to human PPP1R12A (protein phosphatase 1 regulatory subunit 12A); PARTICIPATES IN long term potentiation; INTERACTS WITH (R)-noradrenaline; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 1-octadec-9-enoylglycero-3-phosphate.
Zc3h12a [Search on AGR]
Rattus norvegicus Predicted to enable several functions, including RNA nuclease activity; nucleic acid binding activity; and ribosome binding activity. Predicted to contribute to cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including positive regulation of cellular catabolic process; regulation of gene expression; and regulation of intracellular signal transduction. Predicted to be located in several cellular components, including P-body; nucleoplasm; and rough endoplasmic reticulum membrane. Predicted to be part of protein-containing complex. Human ortholog(s) of this gene implicated in hepatitis B. Orthologous to human ZC3H12A (zinc finger CCCH-type containing 12A); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Il27 [Search on AGR]
Homo sapiens The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008]