pinn-4

Caenorhabditis elegans

Predicted to enable DNA binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in rRNA processing. Located in plasma membrane. Expressed in head; intestinal cell; and tail. Is an ortholog of human PIN4 (peptidylprolyl cis/trans isomerase, NIMA-interacting 4).

CJA18403

Caenorhabditis japonica

Is an ortholog of C. elegans Y48C3A.5.

CRE04016

Caenorhabditis remanei

Is an ortholog of C. elegans Y48C3A.5.

CBN19574

Caenorhabditis brenneri

Is an ortholog of C. elegans Y48C3A.5.

CBG20803

Caenorhabditis briggsae

Is an ortholog of C. elegans Y48C3A.5.

CJA17035

Caenorhabditis japonica

Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans Y48C3A.12; Y48C3A.20; and tsct-1.

CBN13142

Caenorhabditis brenneri

Is an ortholog of C. elegans Y48C3A.5.

col-16

Caenorhabditis elegans

Bm6652

Brugia malayi

Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18.

CBN20292

Caenorhabditis brenneri

Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18.

CJA06822

Caenorhabditis japonica

Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18.

CBG20783

Caenorhabditis briggsae

Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18.

CBN06828

Caenorhabditis brenneri

Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18.

CRE04025

Caenorhabditis remanei

Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18.

C33B4.9

Caenorhabditis elegans

Is affected by spt-16 based on RNA-seq studies.

C53H9.4

Caenorhabditis elegans

Is affected by daf-16 based on RNA-seq studies.

T08G5.4

Caenorhabditis elegans

Is affected by daf-16 based on RNA-seq studies.

ZK287.15

Caenorhabditis elegans

Is affected by spt-16 based on RNA-seq studies.

C55C3.72

Caenorhabditis elegans

Is affected by daf-16 based on RNA-seq studies.

Y43F8B.26

Caenorhabditis elegans

Is affected by spt-16 based on RNA-seq studies.

Y67A6A.3

Caenorhabditis elegans

Is affected by spt-16 based on RNA-seq studies.

21ur-13684

Caenorhabditis elegans

Is affected by spt-16 based on RNA-seq studies.

21ur-5677

Caenorhabditis elegans

Is affected by spt-16 based on RNA-seq studies.

C28D4.11

Caenorhabditis elegans

Is affected by daf-16 based on RNA-seq studies.

F23B12.10

Caenorhabditis elegans

Is affected by spt-16 based on RNA-seq studies.

T08G5.13

Caenorhabditis elegans

Is affected by mut-16 based on RNA-seq studies.

21ur-12752

Caenorhabditis elegans

Is affected by spt-16 based on RNA-seq studies.

OVOC1560

Onchocerca volvulus

Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18.

TMUE_2000007318

Trichuris muris

Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18.

mct-3

Caenorhabditis elegans

Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Expressed in hypodermis. Is an ortholog of human SLC16A14 (solute carrier family 16 member 14); SLC16A4 (solute carrier family 16 member 4); and SLC16A9 (solute carrier family 16 member 9).

Y46C8AL.12

Caenorhabditis elegans

Is affected by daf-2 and daf-16 based on microarray studies.

CBG20787

Caenorhabditis briggsae

Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans Y48C3A.12.

CBG20790

Caenorhabditis briggsae

Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans Y48C3A.12.

21ur-2175

Caenorhabditis elegans

Is affected by hmg-4 and spt-16 based on RNA-seq studies.

F32A11.9

Caenorhabditis elegans

Is affected by tdp-1 and spt-16 based on RNA-seq studies.

CRE04021

Caenorhabditis remanei

Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans Y48C3A.12.

F31F6.15

Caenorhabditis elegans

Is affected by prg-1 and spt-16 based on RNA-seq studies.

mel-16

Caenorhabditis elegans

Acts upstream of or within embryo development.

F56A12.9

Caenorhabditis elegans

Is affected by cep-1 and spt-16 based on RNA-seq studies.

21ur-12364

Caenorhabditis elegans

Is affected by hmg-4 and spt-16 based on RNA-seq studies.

C12D8.23

Caenorhabditis elegans

Is affected by hmg-4 and spt-16 based on RNA-seq studies.

Y39A1A.25

Caenorhabditis elegans

Is affected by daf-16 and dlc-1 based on RNA-seq studies.

21ur-11729

Caenorhabditis elegans

Is affected by hmg-3 and spt-16 based on RNA-seq studies.

21ur-2446

Caenorhabditis elegans

Is affected by hmg-3 and spt-16 based on RNA-seq studies.

sec-16A.1

Caenorhabditis elegans

Involved in endoplasmic reticulum to Golgi vesicle-mediated transport and protein localization to endoplasmic reticulum exit site. Located in endoplasmic reticulum exit site. Is an ortholog of human SEC16A (SEC16 homolog A, endoplasmic reticulum export factor).

F40E3.7

Caenorhabditis elegans

Is affected by several genes including daf-16; hpl-2; and mut-16 based on tiling array and RNA-seq studies. Is affected by Sodium Chloride; Tunicamycin; and paraquat based on RNA-seq and microarray studies.

B0280.6

Caenorhabditis elegans

Is affected by daf-16 and sir-2.1 based on RNA-seq and microarray studies.

C25F6.14

Caenorhabditis elegans

Is affected by daf-12; daf-16; and dpy-21 based on RNA-seq studies.

F08H9.11

Caenorhabditis elegans

Is affected by daf-16; sftb-1; and etr-1 based on RNA-seq studies.

F09F9.12

Caenorhabditis elegans

Is affected by hmg-3; hmg-4; and spt-16 based on RNA-seq studies.

K09H11.14

Caenorhabditis elegans

Is affected by hmg-3; hmg-4; and spt-16 based on RNA-seq studies.

T26G10.6

Caenorhabditis elegans

Is affected by daf-16; dpy-21; and eat-2 based on RNA-seq studies.

21ur-15583

Caenorhabditis elegans

Is affected by lem-2; emr-1; and spt-16 based on RNA-seq studies.

D2023.15

Caenorhabditis elegans

Is affected by hmg-3; hmg-4; and spt-16 based on RNA-seq studies.

CJA05860

Caenorhabditis japonica

Is predicted to encode a protein with the following domain: tRNA pseudouridine synthase Pus10-like. Is an ortholog of C. elegans Y48C3A.20.

PPA37079

Pristionchus pacificus

Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans Y48C3A.12 and tsct-1.

F31D4.11

Caenorhabditis elegans

Is affected by daf-16 and elli-1 based on RNA-seq and microarray studies.

K02E11.8

Caenorhabditis elegans

Is affected by clk-1 and daf-16 based on microarray and RNA-seq studies.

T28D6.15

Caenorhabditis elegans

Is affected by cep-1; spt-16; and blmp-1 based on RNA-seq studies.

C40H1.10

Caenorhabditis elegans

Is affected by tdp-1; hmg-3; and spt-16 based on RNA-seq studies.

F35E12.12

Caenorhabditis elegans

Is affected by cep-1; spt-16; and set-2 based on RNA-seq studies.

R01E6.14

Caenorhabditis elegans

Is affected by tdp-1; hmg-3; and spt-16 based on RNA-seq studies.

21ur-15033

Caenorhabditis elegans

Is affected by emr-1; hmg-3; and spt-16 based on RNA-seq studies.

F49E10.18

Caenorhabditis elegans

Is affected by daf-12; daf-16; and dpy-21 based on RNA-seq studies.

W06A7.6

Caenorhabditis elegans

Is affected by cep-1; spt-16; and adr-1 based on RNA-seq studies.

Bm5821

Brugia malayi

Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans Y48C3A.12 and tsct-1.

TMUE_3000014236

Trichuris muris

Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans Y48C3A.12 and tsct-1.

OVOC3518

Onchocerca volvulus

Predicted to be involved in regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans Y48C3A.12 and tsct-1.

mct-4

Caenorhabditis elegans

Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 7 and lymphangioleiomyomatosis. Is an ortholog of several human genes including SLC16A1 (solute carrier family 16 member 1); SLC16A7 (solute carrier family 16 member 7); and SLC16A8 (solute carrier family 16 member 8).

F22D6.17

Caenorhabditis elegans

Is affected by clk-1; daf-16; and daf-2 based on microarray and RNA-seq studies.

CRE04020

Caenorhabditis remanei

Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Is an ortholog of C. elegans Y48C3A.20.

lin-16

Caenorhabditis elegans

F32F2.2

Caenorhabditis elegans

Is affected by daf-16; adr-1; and ifo-1 based on RNA-seq and microarray studies.

C39E9.18

Caenorhabditis elegans

Is affected by spt-16; sir-2.1; and let-60 based on RNA-seq and microarray studies.

CBN25939

Caenorhabditis brenneri

Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Is an ortholog of C. elegans Y48C3A.20.

PPA28175

Pristionchus pacificus

Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Is an ortholog of C. elegans Y48C3A.20.

K08E5.4

Caenorhabditis elegans

Is affected by daf-16; etr-1; and mrps-5 based on RNA-seq and microarray studies.

Y51B9A.14

Caenorhabditis elegans

Is affected by daf-2; sir-2.1; and daf-16 based on RNA-seq and microarray studies.

CBG20788

Caenorhabditis briggsae

Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Is an ortholog of C. elegans Y48C3A.20.

CBG20791

Caenorhabditis briggsae

Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Is an ortholog of C. elegans Y48C3A.20.

mct-6

Caenorhabditis elegans

Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Expressed in tail. Human ortholog(s) of this gene implicated in cataract 47; familial hyperinsulinemic hypoglycemia 7; and lymphangioleiomyomatosis. Is an ortholog of several human genes including SLC16A1 (solute carrier family 16 member 1); SLC16A6 (solute carrier family 16 member 6); and SLC16A7 (solute carrier family 16 member 7).

sma-16

Caenorhabditis elegans

Acts upstream of or within nematode male tail tip morphogenesis.

gon-16

Caenorhabditis elegans

C07E3.17

Caenorhabditis elegans

Is affected by several genes including daf-16; skn-1; and dpy-21 based on RNA-seq studies.

F49H12.12

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and prg-1 based on RNA-seq studies.

R03D7.9

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies.

sls-1.11

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies.

sls-1.2

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies.

ZK377.4

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies.

F40G12.13

Caenorhabditis elegans

Is affected by several genes including daf-16; dlc-1; and etr-1 based on RNA-seq studies.

F53B2.7

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-18; and atfs-1 based on RNA-seq studies.

sls-1.3

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies.

Y53F4B.40

Caenorhabditis elegans

Is affected by several genes including mut-16; adr-1; and meg-3 based on RNA-seq studies.

ZK380.3

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies.

F25G6.12

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq studies.

sls-1.4

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies.

sls-1.6

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies.

srd-62

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and pgl-1 based on RNA-seq studies.

T27E4.22

Caenorhabditis elegans

Is affected by several genes including daf-16; cep-1; and dpy-21 based on RNA-seq studies.

Y75B8A.41

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and cat-2 based on RNA-seq studies.

che-16

Caenorhabditis elegans

sls-1.10

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies.

sls-1.8

Caenorhabditis elegans

Is affected by several genes including daf-16; sek-1; and pgl-1 based on RNA-seq studies.

T06D8.11

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies.

T14F9.9

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq studies.

Y50E8A.19

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and hsf-1 based on RNA-seq studies.

B0513.12

Caenorhabditis elegans

Is affected by several genes including daf-16; ahr-1; and mrps-5 based on RNA-seq studies.

sls-1.7

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies.

ZC513.16

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies.

bus-16

Caenorhabditis elegans

T06A1.6

Caenorhabditis elegans

Enriched in sensory neurons based on RNA-seq studies. Is affected by daf-16 based on RNA-seq studies.

Bm6653

Brugia malayi

Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Is an ortholog of C. elegans Y48C3A.20.

OVOC10270

Onchocerca volvulus

Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Is an ortholog of C. elegans Y48C3A.20.

TMUE_2000006994

Trichuris muris

Predicted to enable RNA binding activity and pseudouridine synthase activity. Predicted to be involved in pseudouridine synthesis. Is an ortholog of C. elegans Y48C3A.20.

AC8.6

Caenorhabditis elegans

Is affected by several genes including daf-16; let-60; and sir-2.1 based on microarray and RNA-seq studies.

W09C2.9

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies.

F15A8.9

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies.

miro-2

Caenorhabditis elegans

Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on RNA-seq and microarray studies.

sls-1.9

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and sek-1 based on RNA-seq and microarray studies.

Y67D2.8

Caenorhabditis elegans

Enriched in AFD and ASER based on RNA-seq studies. Is affected by daf-16 based on RNA-seq studies.

Y71A12B.21

Caenorhabditis elegans

Is affected by several genes including daf-16; clk-1; and prg-1 based on RNA-seq and microarray studies.

AC3.13

Caenorhabditis elegans

Is affected by several genes including daf-16; clk-1; and hsp-6 based on microarray and RNA-seq studies.

T05A6.10

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies.

Y51H4A.20

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies.

Y54G9A.8

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq and microarray studies.

nspa-12

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and pgl-1 based on microarray and RNA-seq studies.

scl-4

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and ung-1 based on microarray and tiling array studies.

T04A11.14

Caenorhabditis elegans

Is affected by several genes including daf-16; lin-4; and lin-14 based on RNA-seq and microarray studies.

T05A6.18

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies.

T16H12.13

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies.

W06G6.16

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray and RNA-seq studies.

ZK185.10

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies.

M04B2.12

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies.

M02F4.9

Caenorhabditis elegans

Is affected by several genes including mut-16; etr-1; and swsn-1 based on tiling array and RNA-seq studies.

F19C7.4

Caenorhabditis elegans

Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human PRSS16 (serine protease 16).

Y24D9A.10

Caenorhabditis elegans

Is affected by several genes including daf-16; hpl-2; and hmg-3 based on tiling array and RNA-seq studies.

Y75B7AL.5

Caenorhabditis elegans

Enriched in AFD; ASER; and PLM based on RNA-seq studies. Is affected by daf-16 based on RNA-seq studies.

F19C7.2

Caenorhabditis elegans

Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Is an ortholog of human PRSS16 (serine protease 16).

let-75

Caenorhabditis elegans

Is affected by several genes including hpl-2; mut-16; and pry-1 based on microarray; RNA-seq; and proteomic studies.

21ur-13453

Caenorhabditis elegans

Is affected by daf-16 and blmp-1 based on RNA-seq studies. Is affected by juglone based on RNA-seq studies.

ZC455.15

Caenorhabditis elegans

Is affected by daf-16 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.

OVOC11493

Onchocerca volvulus

Is predicted to encode a protein with the following domains: Thioredoxin-like fold and Glutathione S-transferase N-terminal domain. Is an ortholog of C. elegans Y48C3A.3.

inx-16

Caenorhabditis elegans

Predicted to enable gap junction hemi-channel activity. Involved in calcium-mediated signaling; regulation of defecation rhythm; and regulation of neuromuscular synaptic transmission. Located in gap junction. Expressed in intestine.

T28D9.11

Caenorhabditis elegans

Is affected by several genes including daf-16; clk-1; and pgl-1 based on tiling array; RNA-seq; and microarray studies.

W04D2.7

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and hpl-2 based on tiling array; RNA-seq; and microarray studies.

Y32H12A.9

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and clk-1 based on tiling array; microarray; and RNA-seq studies.

klp-16

Caenorhabditis elegans

Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in chromosome segregation. Located in neuronal cell body. Expressed in several structures, including ABa; EMS; Psub2; germ line; and head.

21ur-4206

Caenorhabditis elegans

Is affected by spt-16 and rnp-6 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies.

K12H4.7

Caenorhabditis elegans

Predicted to enable dipeptidyl-peptidase activity. Involved in innate immune response. Expressed in intestine. Is an ortholog of human PRSS16 (serine protease 16).

21ur-4710

Caenorhabditis elegans

Is affected by spt-16 and rnp-6 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies.

K09E9.12

Caenorhabditis elegans

Enriched in AFD; ASER; PLM; and sensory neurons based on RNA-seq studies. Is affected by daf-16 based on RNA-seq studies.

PPA47061

Pristionchus pacificus

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

nlp-16

Caenorhabditis elegans

Expressed in head neurons; intestine; and lateral ganglion. Is predicted to encode a protein with the following domain: Phosphorylation site.

zhp-4

Caenorhabditis elegans

Predicted to enable SUMO transferase activity. Predicted to be involved in homologous chromosome pairing at meiosis and protein sumoylation. Predicted to be located in synaptonemal complex. Human ortholog(s) of this gene implicated in spermatogenic failure 62. Is an ortholog of human RNF212 (ring finger protein 212).

ceh-16

Caenorhabditis elegans

Enables sequence-specific DNA binding activity. Involved in several processes, including embryonic body morphogenesis; epidermal cell fate specification; and regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including ABarpa; AIZ; hyp5; retrovesicular ganglion neurons; and seam cell. Human ortholog(s) of this gene implicated in Parkinson's disease and autistic disorder. Is an ortholog of human EN1 (engrailed homeobox 1) and EN2 (engrailed homeobox 2).

daf-16

Caenorhabditis elegans

Enables several functions, including 14-3-3 protein binding activity; beta-catenin binding activity; and enzyme binding activity. Involved in several processes, including defense response to other organism; regulation of dauer larval development; and regulation of gene expression. Located in cytosol and nucleus. Expressed in several structures, including germ cell; gonad; hypodermis; neurons; and somatic cell. Used to study Parkinson's disease and diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; alveolar rhabdomyosarcoma; reproductive organ cancer (multiple); and rheumatoid arthritis. Is an ortholog of human FOXO4 (forkhead box O4).

Bm6649

Brugia malayi

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

CBG20786

Caenorhabditis briggsae

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

srz-57

Caenorhabditis elegans

Is affected by let-60; daf-2; and daf-16 based on microarray studies. Is affected by resveratrol and Sirolimus based on microarray studies.

CJA15181

Caenorhabditis japonica

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

TMUE_2000009431

Trichuris muris

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

tbc-16

Caenorhabditis elegans

Predicted to enable GTPase activator activity. Predicted to be located in early endosome. Is an ortholog of human TBC1D16 (TBC1 domain family member 16).

Y55B1BR.7

Caenorhabditis elegans

Enriched in AFD; ASER; and PLM based on RNA-seq studies. Is affected by daf-16 and camt-1 based on RNA-seq studies.

mct-5

Caenorhabditis elegans

Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in cataract 47; familial hyperinsulinemic hypoglycemia 7; and lymphangioleiomyomatosis. Is an ortholog of human SLC16A12 (solute carrier family 16 member 12) and SLC16A8 (solute carrier family 16 member 8).

OVOC10269

Onchocerca volvulus

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

PPA47059

Pristionchus pacificus

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

PPA47060

Pristionchus pacificus

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

SRAE_0000014150

Strongyloides ratti

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

cyn-16

Caenorhabditis elegans

Enables peptidyl-prolyl cis-trans isomerase activity. Predicted to be part of catalytic step 2 spliceosome. Expressed in intestine and ventral cord neurons. Is an ortholog of human CWC27 (CWC27 spliceosome associated cyclophilin).

set-16

Caenorhabditis elegans

Enables histone H3K4 methyltransferase activity. Involved in programmed cell death and regulation of vulval development. Part of MLL3/4 complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P8.p hermaphrodite; and linker cell. Human ortholog(s) of this gene implicated in several diseases, including Kabuki syndrome; Kleefstra syndrome 2; and carcinoma (multiple). Is an ortholog of human KMT2D (lysine methyltransferase 2D).

F20G2.9

Caenorhabditis elegans

Is affected by spt-16; pmt-2; and ikb-1 based on RNA-seq and microarray studies. Is affected by Cry5B based on microarray studies.

pcp-3

Caenorhabditis elegans

Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. Is an ortholog of human PRSS16 (serine protease 16).

Y105E8B.10

Caenorhabditis elegans

Is affected by daf-16 based on RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies.

pcp-4

Caenorhabditis elegans

Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. Is an ortholog of human PRSS16 (serine protease 16).

F28F9.11

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq studies.

ptr-16

Caenorhabditis elegans

Predicted to be involved in endocytosis and molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human PTCHD1 (patched domain containing 1); PTCHD3 (patched domain containing 3 (gene/pseudogene)); and PTCHD4 (patched domain containing 4).

F57G12.10

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies.

Y51H4A.19

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. Is affected by cadmium based on microarray studies.

CBG31011

Caenorhabditis briggsae

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

CBN30446

Caenorhabditis brenneri

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

CJA28829

Caenorhabditis japonica

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

CRE04022

Caenorhabditis remanei

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

SRAE_2000344000

Strongyloides ratti

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change. Is an ortholog of C. elegans Y48C3A.14.

linc-113

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq studies.

npr-16

Caenorhabditis elegans

Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in neuron projection. Expressed in anal depressor muscle; neurons; ventral nerve cord; and vm1. Is an ortholog of human SSTR3 (somatostatin receptor 3).

mut-16

Caenorhabditis elegans

Involved in obsolete negative regulation of transposition, DNA-mediated; regulatory ncRNA-mediated post-transcriptional gene silencing; and siRNA processing. Located in mutator focus and nucleus. Expressed in several structures, including germ cell; germ line; and somatic cell.

F40G12.14

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; dlc-1; and etr-1 based on RNA-seq studies.

linc-125

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq studies. Is affected by antimycin based on RNA-seq studies.

Y17D7B.9

Caenorhabditis elegans

Is affected by daf-16; sir-2.1; and spg-7 based on RNA-seq and microarray studies. Is affected by Cry5B and Sirolimus based on microarray studies.

vps-16

Caenorhabditis elegans

Predicted to enable actin binding activity. Involved in digestive tract development and embryo development. Predicted to be located in endosome. Predicted to be part of HOPS complex. Human ortholog(s) of this gene implicated in dystonia. Is an ortholog of human VPS16 (VPS16 core subunit of CORVET and HOPS complexes).

C08F11.116

Caenorhabditis elegans

Is affected by several genes including daf-16; cep-1; and hmg-3 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies.

2RSSE.3

Caenorhabditis elegans

Is affected by several genes including daf-16; sek-1; and pgl-1 based on RNA-seq studies. Is affected by cadmium based on RNA-seq studies.

C14A6.9

Caenorhabditis elegans

Is affected by several genes including daf-16; bar-1; and wdr-5.1 based on microarray and RNA-seq studies. Is affected by allantoin based on microarray studies.

T19H12.12

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Tunicamycin based on microarray studies.

Y73B3A.2

Caenorhabditis elegans

Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and eat-2 based on RNA-seq studies.

B0513.7

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies.

C46F4.3

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq and microarray studies. Is affected by Tunicamycin based on microarray studies.

F29C12.7

Caenorhabditis elegans

Is affected by several genes including daf-16; fbf-1; and nuo-6 based on RNA-seq and microarray studies. Is affected by Cry5B based on microarray studies.

fbxc-16

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and mex-3 based on RNA-seq and microarray studies. Is affected by Sirolimus based on microarray studies.

mct-1

Caenorhabditis elegans

Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Expressed in pharynx. Is an ortholog of human SLC16A4 (solute carrier family 16 member 4).

srh-189

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and lin-4 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies.

21ur-13425

Caenorhabditis elegans

Is affected by several genes including daf-16; cpl-1; and blmp-1 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies.

F54B8.17

Caenorhabditis elegans

Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies.

R08B4.9

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies.

Y105C5A.20

Caenorhabditis elegans

Is affected by daf-16 and eat-2 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

Y46H3C.4

Caenorhabditis elegans

Is affected by several genes including daf-16; nhl-2; and emb-4 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies.

3R5.2

Caenorhabditis elegans

Is affected by several genes including daf-16; clk-1; and sek-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies.

clec-14

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by Ethanol based on microarray studies.

F32A11.4

Caenorhabditis elegans

Is affected by several genes including daf-16; clk-1; and alg-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies.

F41D3.8

Caenorhabditis elegans

Is affected by several genes including daf-16; sir-2.1; and cyc-1 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies.

nspc-11

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and clk-1 based on microarray and RNA-seq studies. Is affected by triclosan based on microarray studies.

Y40H7A.7

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies.

clec-23

Caenorhabditis elegans

Is affected by several genes including daf-16; clk-1; and smg-2 based on microarray and RNA-seq studies. Is affected by nitroguanidine based on microarray studies.

Y105C5A.19

Caenorhabditis elegans

Is affected by daf-16 and eat-2 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

Y43D4A.7

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by nitroguanidine based on microarray studies.

C08B6.15

Caenorhabditis elegans

Is affected by tatn-1; daf-2; and mut-16 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.

F56F10.1

Caenorhabditis elegans

Predicted to enable dipeptidyl-peptidase activity. Involved in innate immune response. Located in membrane raft. Is an ortholog of human PRSS16 (serine protease 16).

K08F4.13

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and hsf-1 based on RNA-seq and microarray studies. Is affected by Amygdalin based on RNA-seq studies.

Y11D7A.1

Caenorhabditis elegans

Is affected by several genes including daf-16; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by bortezomib based on RNA-seq studies.

linc-107

Caenorhabditis elegans

Is affected by several genes including daf-16; skn-1; and daf-12 based on RNA-seq studies. Is affected by stavudine and paraquat based on RNA-seq studies.

R10E8.10

Caenorhabditis elegans

Enriched in AFD; ASER; and intestine based on RNA-seq studies. Is affected by several genes including daf-16; hda-2; and hlh-26 based on RNA-seq studies.

Y80D3A.11

Caenorhabditis elegans

Is affected by several genes including daf-16; skn-1; and hpl-2 based on RNA-seq studies. Is affected by allantoin and Sirolimus based on RNA-seq studies.

ins-16

Caenorhabditis elegans

Expressed in distal tip cell; intestine; neurons; and pharynx. Is predicted to encode a protein with the following domain: Insulin-like superfamily.

W05H12.3

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. Is affected by Psoralens and allantoin based on RNA-seq studies.

F53B2.1

Caenorhabditis elegans

Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on proteomic; microarray; and RNA-seq studies. Is affected by resveratrol based on microarray studies.

srw-65

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; hpl-2; and rsr-2 based on tiling array and RNA-seq studies.

tmem-138

Caenorhabditis elegans

Located in ciliary transition zone. Expressed in ciliated neurons. Human ortholog(s) of this gene implicated in Joubert syndrome 16. Is an ortholog of human TMEM138 (transmembrane protein 138).

Y94H6A.17

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by Doxycycline based on RNA-seq studies.

F22B8.2

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and hpl-2 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.

linc-68

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by graphene oxide based on RNA-seq studies.

Y51H4A.18

Caenorhabditis elegans

Is affected by several genes including daf-16; pmk-1; and pgl-1 based on RNA-seq and microarray studies. Is affected by Atrazine and cadmium based on microarray studies.

CBN32330

Caenorhabditis brenneri

Predicted to enable DNA binding activity and DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA topological change and regulation of transcription by RNA polymerase II. Is an ortholog of C. elegans Y48C3A.14.

F10D7.5

Caenorhabditis elegans

Predicted to enable ubiquitin protein ligase activity. Is an ortholog of human NEURL1 (neuralized E3 ubiquitin protein ligase 1) and NEURL1B (neuralized E3 ubiquitin protein ligase 1B).

skr-16

Caenorhabditis elegans

Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1).

srx-49

Caenorhabditis elegans

Is affected by rsr-2 and spt-16 based on tiling array and RNA-seq studies. Is affected by Mercuric Chloride and adsorbable organic bromine compound based on microarray studies.

T08G5.11

Caenorhabditis elegans

Is affected by several genes including daf-16; meg-3; and meg-4 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.

Y73B3A.17

Caenorhabditis elegans

Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; egl-9; and hlh-2 based on RNA-seq and microarray studies.

C54F6.2

Caenorhabditis elegans

Is affected by daf-16; eat-2; and sams-3 based on RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

F35F10.10

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by resveratrol based on microarray studies.

AC8.9

Caenorhabditis elegans

Is affected by several genes including daf-16; hsf-1; and sek-1 based on RNA-seq and microarray studies. Is affected by Chlorpyrifos and Diazinon based on microarray studies.

K08D9.5

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and eat-2 based on microarray and RNA-seq studies. Is affected by Sirolimus and allantoin based on microarray studies.

F54D8.10

Caenorhabditis elegans

Is affected by several genes including daf-16; unc-30; and nhr-8 based on RNA-seq studies. Is affected by atracurium; bortezomib; and Tamoxifen based on RNA-seq studies.

H28G03.5

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies.

spp-30

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and csr-1 based on RNA-seq studies. Is predicted to encode a protein with the following domain: Saposin-like.

Y113G7A.2

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and let-418 based on RNA-seq studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies.

Y38C1AB.7

Caenorhabditis elegans

Is affected by several genes including daf-16; clk-1; and isp-1 based on microarray; RNA-seq; and proteomic studies. Is affected by Rifampin based on RNA-seq studies.

AC8.2

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by methylmercuric chloride and Diazinon based on microarray studies.

T07H8.11

Caenorhabditis elegans

Is affected by several genes including daf-16; skn-1; and xbp-1 based on RNA-seq and microarray studies. Is affected by CGP37157 and bortezomib based on RNA-seq studies.

nas-16

Caenorhabditis elegans

Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. Expressed in intestine.

srh-158

Caenorhabditis elegans

Is affected by daf-16; bet-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies.

W07G4.7

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray and RNA-seq studies. Is affected by tryptophan and dafa#1 based on microarray studies.

D2045.7

Caenorhabditis elegans

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in phosphorylation. Predicted to be located in Golgi apparatus. Is an ortholog of human STK16 (serine/threonine kinase 16).

F17C11.20

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies. Is affected by bisphenol A and bisphenol S based on RNA-seq studies.

lfor-2

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. Is affected by Ethanol and Tunicamycin based on RNA-seq and microarray studies.

T03E6.2

Caenorhabditis elegans

Is affected by several genes including daf-16; clk-1; and mir-34 based on microarray and tiling array studies. Is affected by adsorbable organic bromine compound based on microarray studies.

B0250.3

Caenorhabditis elegans

Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and unc-30 based on RNA-seq studies.

C04E12.6

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Tunicamycin; resveratrol; and Sirolimus based on microarray studies.

F21H12.2

Caenorhabditis elegans

Enriched in dopaminergic neurons and neurons based on tiling array studies. Is affected by several genes including daf-16; sir-2.1; and pqm-1 based on microarray and RNA-seq studies.

pcp-2

Caenorhabditis elegans

Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Located in membrane raft. Is an ortholog of human PRSS16 (serine protease 16).

Y108F1.1

Caenorhabditis elegans

Is affected by several genes including daf-16; sek-1; and isp-1 based on RNA-seq and microarray studies. Is affected by cadmium; Sirolimus; and allantoin based on microarray studies.

Y57E12AL.3

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and hsf-1 based on microarray and RNA-seq studies. Is affected by Rifampin and allantoin based on RNA-seq studies.

ZC239.1

Caenorhabditis elegans

Is affected by several genes including eat-2; clk-1; and mut-16 based on RNA-seq and microarray studies. Is affected by Rifampin and allantoin based on RNA-seq studies.

Y45G12C.16

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and hsf-1 based on RNA-seq; proteomic; and microarray studies. Is affected by CGP37157 and Ketamine based on RNA-seq studies.

cyp-13A9

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and nhr-49 based on RNA-seq and microarray studies. Is affected by paraquat; bortezomib; and cadmium based on RNA-seq studies.

W09C2.8

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by stearic acid and sucrose based on RNA-seq studies.

ZK892.8

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and etr-1 based on RNA-seq and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies.

liv-5

Caenorhabditis elegans

R03H10.11

Caenorhabditis elegans

Is affected by several genes including daf-16; eri-1; and rrf-1 based on RNA-seq and microarray studies. Is affected by paraquat; dafa#1; and Sirolimus based on microarray studies.

Y71A12B.14

Caenorhabditis elegans

Enriched in AVK and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies.

C41G7.15

Caenorhabditis elegans

Enriched in g1AL; g1AR; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by spt-16; set-2; and lpd-3 based on RNA-seq studies.

sls-1.12

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.

Y71A12B.3

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.

linc-34

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and cep-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube and paraquat based on RNA-seq studies.

unc-16

Caenorhabditis elegans

Enables kinase binding activity; kinesin binding activity; and signaling adaptor activity. Involved in several processes, including defecation; egg-laying behavior; and regulation of JNK cascade. Located in axon; cell body; and cytoplasm. Expressed in body wall musculature; hypodermis; intestine; and nervous system. Human ortholog(s) of this gene implicated in endometrial cancer; hepatocellular carcinoma; and liver cirrhosis. Is an ortholog of human MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3).

acr-16

Caenorhabditis elegans

Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in monoatomic ion transmembrane transport. Located in cell projection. Expressed in body wall musculature; linker cell; muscle cell; and neurons. Used to study nicotine dependence. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit).

C08H9.9

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and smg-2 based on RNA-seq and microarray studies. Is affected by adsorbable organic bromine compound and Sirolimus based on microarray studies.

F56B3.3

Caenorhabditis elegans

Is affected by several genes including sir-2.1; hrde-1; and mut-16 based on RNA-seq and microarray studies. Is affected by cholesterol and Atrazine based on RNA-seq and microarray studies.

Y102A5C.38

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and sek-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq studies.

F07G11.7

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray and RNA-seq studies. Is affected by single-walled carbon nanotube and Sirolimus based on microarray studies.

Y95D11A.2

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and unc-30 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

B0379.6

Caenorhabditis elegans

Is affected by several genes including daf-16; hpl-2; and cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies.

F01G10.11

Caenorhabditis elegans

Is affected by several genes including daf-16; dcr-1; and bar-1 based on microarray studies. Is affected by seven chemicals including Heme; Humic Substances; and copper sulfate based on microarray studies.

srg-49

Caenorhabditis elegans

Is affected by several genes including daf-16; wdr-23; and smn-1 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies.

srw-70

Caenorhabditis elegans

Is affected by several genes including daf-16; sir-2.1; and mdt-15 based on microarray and tiling array studies. Is affected by resveratrol; tetrabromobisphenol A; and dafa#1 based on microarray studies.

Y51A2D.23

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies.

C53B7.6

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and clk-1 based on tiling array; RNA-seq; and microarray studies. Is affected by methylmercuric chloride and Tunicamycin based on microarray studies.

C56A3.10

Caenorhabditis elegans

Is affected by several genes including daf-16; met-2; and set-25 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

ZK1225.7

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and unc-30 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

liv-2

Caenorhabditis elegans

H15N14.4

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies.

Y116F11B.13

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and mex-1 based on microarray and RNA-seq studies. Is affected by allantoin; Sirolimus; and cadmium based on RNA-seq and microarray studies.

ZK384.7

Caenorhabditis elegans

Enriched in PVM; amphid neurons; and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including rrf-3; unc-30; and mut-16 based on RNA-seq studies.

his-16

Caenorhabditis elegans

Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in defense response to Gram-negative bacterium and innate immune response. Predicted to be part of nucleosome. Human ortholog(s) of this gene implicated in oral mucosa leukoplakia and oral squamous cell carcinoma. Is an ortholog of human H2AX (H2A.X variant histone).

mct-2

Caenorhabditis elegans

Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Is an ortholog of human SLC16A4 (solute carrier family 16 member 4).

Y75B12A.1

Caenorhabditis elegans

Is affected by several genes including daf-16; glp-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by Rifampin; allantoin; and Cholestanol based on RNA-seq and microarray studies.

clec-16

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-18; and rrf-1 based on RNA-seq and microarray studies. Is affected by five chemicals including cadmium; Colistin; and 2 based on microarray studies.

clec-220

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq and microarray studies. Is affected by methylmercuric chloride and Ketamine based on microarray and RNA-seq studies.

Y53F4B.38

Caenorhabditis elegans

Is affected by several genes including hpl-2; mut-16; and smg-2 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube and Doxycycline based on RNA-seq studies.

F41E7.20

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by four chemicals including bortezomib; Doxycycline; and Tamoxifen based on RNA-seq studies.

K08E7.10

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies.

W06G6.17

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

Y64H9A.1

Caenorhabditis elegans

Enriched in intestine based on microarray studies. Is affected by several genes including daf-16; clk-1; and drh-3 based on microarray and RNA-seq studies. Is affected by Diazinon based on microarray studies.

C43D7.1

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies.

F56A12.10

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; dpy-21; and his-3 based on RNA-seq studies. Is affected by paraquat based on RNA-seq studies.

Y116F11B.10

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Zidovudine; Sirolimus; and metformin based on RNA-seq studies.

ZK938.8

Caenorhabditis elegans

Is affected by several genes including daf-16; smn-1; and mrps-5 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies.

gpa-16

Caenorhabditis elegans

Predicted to enable several functions, including G-protein beta/gamma-subunit complex binding activity; GTPase activity; and guanyl ribonucleotide binding activity. Involved in embryonic axis specification and establishment of mitotic spindle orientation. Located in cell cortex. Expressed in several structures, including Psub4; Z2; Z3; neurons; and pharynx. Human ortholog(s) of this gene implicated in achromatopsia 4; congenital stationary night blindness 1G; and congenital stationary night blindness autosomal dominant 3. Is an ortholog of human GNAI1 (G protein subunit alpha i1).

vha-16

Caenorhabditis elegans

Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in vacuolar acidification and vacuolar transport. Predicted to be located in early endosome. Predicted to be part of plasma membrane proton-transporting V-type ATPase complex and vacuolar proton-transporting V-type ATPase complex. Expressed in head and tail. Is an ortholog of human ATP6V0D1 (ATPase H+ transporting V0 subunit d1).

fbxb-16

Caenorhabditis elegans

Enriched in ABalpppapa; ABpraaaapa; GLR; body wall muscle cell; and excretory system based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box domain; F-box associated; and F-box associated domain, type 2.

F18A11.7

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies.

F23D12.9

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq and microarray studies. Is affected by five chemicals including allantoin; metformin; and Rifampin based on RNA-seq studies.

T07D10.10

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by six chemicals including stavudine; Zidovudine; and Psoralens based on RNA-seq studies.

ZK637.18

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

AC3.9

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies.

C23H5.15

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies.

Y116A8A.10

Caenorhabditis elegans

Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

F11A6.3

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

F20B10.2

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and sek-1 based on RNA-seq and microarray studies. Is affected by six chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies.

F36G9.4

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq studies.

srd-76

Caenorhabditis elegans

Enriched in neurons based on microarray studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on microarray and RNA-seq studies. Is affected by allantoin based on microarray studies.

W05H7.2

Caenorhabditis elegans

Is affected by several genes including daf-16; skn-1; and sir-2.1 based on microarray and RNA-seq studies. Is affected by six chemicals including silicon dioxide nanoparticle; Chlorpyrifos; and Diazinon based on microarray studies.

PPA22753

Pristionchus pacificus

Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; and Metaxin, glutathione S-transferase domain. Is an ortholog of C. elegans Y48C3A.3.

liv-4

Caenorhabditis elegans

C06A1.6

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including Neurotoxins; Testosterone; and resveratrol based on microarray studies.

ZK1025.1

Caenorhabditis elegans

Is affected by several genes including daf-16; hsf-1; and eat-2 based on RNA-seq studies. Is affected by eight chemicals including manganese chloride; Alovudine; and Psoralens based on RNA-seq and microarray studies.

gly-16

Caenorhabditis elegans

Predicted to enable glycosyltransferase activity. Predicted to be located in Golgi membrane. Expressed in seam cell. Human ortholog(s) of this gene implicated in cataract 13 with adult i phenotype. Is an ortholog of several human genes including GCNT1 (glucosaminyl (N-acetyl) transferase 1); GCNT3 (glucosaminyl (N-acetyl) transferase 3, mucin type); and GCNT4 (glucosaminyl (N-acetyl) transferase 4).

Y71A12B.13

Caenorhabditis elegans

Enriched in AVK based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies.

F35C5.4

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by clk-1; spt-16; and daf-2 based on microarray and RNA-seq studies. Is affected by resveratrol and tetrabromobisphenol A based on microarray studies.

lfor-1

Caenorhabditis elegans

Enriched in PDB based on single-cell RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and glh-1 based on RNA-seq studies. Is affected by Tunicamycin based on microarray studies.

Y6B3B.2

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including methylmercury hydroxide; Psoralens; and allantoin based on RNA-seq studies.

F33D11.16

Caenorhabditis elegans

Enriched in nerve ring neurons; pharyngeal-intestinal valve; and rectal gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; hda-2; and etr-1 based on RNA-seq studies.

M01G12.8

Caenorhabditis elegans

Is affected by several genes including daf-16; hsf-1; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies.

ttr-4

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies.

F56D6.9

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and glp-1 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including rotenone; Tunicamycin; and indole based on RNA-seq and microarray studies.

CBN12900

Caenorhabditis brenneri

Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Metaxin, glutathione S-transferase domain; and Thioredoxin-like superfamily. Is an ortholog of C. elegans Y48C3A.3.

CBN23178

Caenorhabditis brenneri

Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Metaxin, glutathione S-transferase domain; and Thioredoxin-like superfamily. Is an ortholog of C. elegans Y48C3A.3.

C40H5.8

Caenorhabditis elegans

Is affected by several genes including daf-16; sir-2.1; and hpl-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.

F14E5.7

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and alg-1 based on RNA-seq and microarray studies. Is affected by Humic Substances; paraquat; and silicon dioxide nanoparticle based on microarray and RNA-seq studies.

F47H4.12

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies.

F54F3.2

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by eight chemicals including stavudine; paraquat; and Heme based on RNA-seq and microarray studies.

hpo-41

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies.

F22B8.4

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including rotenone; Alovudine; and stavudine based on RNA-seq and microarray studies.

F41B5.11

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies.

T06G6.11

Caenorhabditis elegans

Is affected by several genes including daf-16; clk-1; and nhr-25 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.

T24A6.17

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies.

Y57G7A.8

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and glp-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.

F20B6.1

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies.

F46A8.1

Caenorhabditis elegans

Is affected by several genes including daf-16; hsf-1; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; paraquat; and CGP37157 based on RNA-seq and microarray studies.

F54D5.16

Caenorhabditis elegans

Is affected by several genes including daf-16; hsf-1; and isp-1 based on RNA-seq and microarray studies. Is affected by six chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies.

fbxa-70

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and hsf-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and Rifampin based on RNA-seq and microarray studies.

math-47

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by six chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies.

Y47D3B.12

Caenorhabditis elegans

Is affected by several genes including daf-16; hsf-1; and rrf-3 based on RNA-seq and microarray studies. Is affected by eight chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies.

CBG20802

Caenorhabditis briggsae

Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Metaxin, glutathione S-transferase domain; and Thioredoxin-like superfamily. Is an ortholog of C. elegans Y48C3A.3.

CJA02532

Caenorhabditis japonica

Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Metaxin, glutathione S-transferase domain; and Thioredoxin-like superfamily. Is an ortholog of C. elegans Y48C3A.3.

CRE04017

Caenorhabditis remanei

Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase N-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Metaxin, glutathione S-transferase domain; and Thioredoxin-like superfamily. Is an ortholog of C. elegans Y48C3A.3.

C06E2.2

Caenorhabditis elegans

Enriched in ADFL; ADFR; AWAL; AWAR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including daf-16; clk-1; and pgrn-1 based on RNA-seq and microarray studies.

F55A12.6

Caenorhabditis elegans

Is affected by several genes including daf-16; skn-1; and clk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including Mercuric Chloride; Psoralens; and allantoin based on microarray and RNA-seq studies.

T26F2.2

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by thirteen chemicals including methylmercuric chloride; stavudine; and Psoralens based on microarray and RNA-seq studies.

ZK112.4

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and ain-1 based on microarray; tiling array; and RNA-seq studies. Is affected by fluoranthene based on microarray studies.

C13A2.2

Caenorhabditis elegans

Enriched in muscle cell based on microarray studies. Is affected by several genes including daf-16; daf-12; and sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by tryptophan based on microarray studies.

T08D2.2

Caenorhabditis elegans

Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Alovudine based on RNA-seq studies.

fbxa-186

Caenorhabditis elegans

Enriched in intestine based on tiling array studies. Is affected by several genes including daf-16; daf-12; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by Tunicamycin based on microarray studies.

W06G6.20

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including D-glucopyranose; Psoralens; and allantoin based on RNA-seq and microarray studies.

Y48A6B.8

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by ten chemicals including Sodium Chloride; Psoralens; and allantoin based on RNA-seq and microarray studies.

C09F9.4

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and sek-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercury hydroxide; Psoralens; and allantoin based on RNA-seq and microarray studies.

C25F6.8

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by ten chemicals including Sodium Chloride; allantoin; and Sirolimus based on RNA-seq and microarray studies.

clec-69

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and dpy-10 based on RNA-seq and microarray studies. Is affected by eighteen chemicals including rotenone; D-glucose; and sesamin based on RNA-seq and microarray studies.

F44D12.11

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by nine chemicals including manganese chloride; Psoralens; and allantoin based on RNA-seq and microarray studies.

C08F11.6

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Alovudine; and allantoin based on RNA-seq studies.

M02E1.3

Caenorhabditis elegans

Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-16; sek-1; and smg-1 based on RNA-seq studies. Is affected by mianserin; Rifampin; and allantoin based on RNA-seq studies.

tsp-20

Caenorhabditis elegans

Predicted to be located in membrane. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex. Is an ortholog of several human genes including CD151 (CD151 molecule (Raph blood group)); CD37 (CD37 molecule); and TSPAN16 (tetraspanin 16).

Y116F11B.6

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including paraquat; stearic acid; and bortezomib based on RNA-seq studies.

ZC116.5

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by six chemicals including rotenone; Sodium Chloride; and Cry5B based on RNA-seq and microarray studies.

C27A7.2

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and rrf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Ethanol; Alovudine; and stavudine based on RNA-seq and microarray studies.

F36D1.12

Caenorhabditis elegans

Enriched in neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; csr-1; and met-2 based on RNA-seq studies. Is affected by tryptophan based on microarray studies.

D2023.8

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; sek-1; and hpl-2 based on RNA-seq studies. Is affected by metformin; cholesterol; and paraquat based on RNA-seq studies.

dhhc-9

Caenorhabditis elegans

Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Is an ortholog of human ZDHHC16 (zinc finger DHHC-type palmitoyltransferase 16).

fbxa-57

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including tryptophan; Psoralens; and allantoin based on microarray and RNA-seq studies.

T09B4.7

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by nine chemicals including Mercuric Chloride; D-glucose; and Rifampin based on microarray and RNA-seq studies.

Y19D10B.4

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and hsf-1 based on RNA-seq and microarray studies. Is affected by five chemicals including multi-walled carbon nanotube; Zidovudine; and graphene oxide based on RNA-seq studies.

BE10.6

Caenorhabditis elegans

Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; aak-2; and prg-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.

C01B12.9

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including rotenone; Tunicamycin; and Cry5B based on RNA-seq and microarray studies.

C38D4.10

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and prg-1 based on RNA-seq studies. Is affected by Rifampin; allantoin; and atracurium based on RNA-seq studies.

B0238.13

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and hsf-1 based on proteomic; microarray; and RNA-seq studies. Is affected by thirteen chemicals including tryptophan; tert-Butylhydroperoxide; and Rifampin based on microarray and RNA-seq studies.

glb-16

Caenorhabditis elegans

Predicted to enable oxygen binding activity and oxygen carrier activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in head neurons and tail neurons.

T23F6.2

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by five chemicals including methylmercury hydroxide; methylmercuric chloride; and Tunicamycin based on RNA-seq and microarray studies.

Y7A9A.79

Caenorhabditis elegans

Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on RNA-seq studies. Is affected by atracurium and paraquat based on RNA-seq studies.

C45E5.3

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies.

K02E11.10

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twenty-five chemicals including hydrogen sulfide; Ethanol; and Nitric Oxide based on microarray and RNA-seq studies.

K03B8.4

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by cadmium and Sirolimus based on microarray studies.

miro-3

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on RNA-seq and microarray studies. Is affected by allantoin; Sirolimus; and Doxycycline based on RNA-seq studies.

pigc-1

Caenorhabditis elegans

Predicted to enable glycosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Located in nucleus. Human ortholog(s) of this gene implicated in glycosylphosphatidylinositol biosynthesis defect 16. Is an ortholog of human PIGC (phosphatidylinositol glycan anchor biosynthesis class C).

spp-29

Caenorhabditis elegans

Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domain: Saposin-like.

Y59E9AR.8

Caenorhabditis elegans

Is affected by several genes including daf-16; skn-1; and sek-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Zc3h12a-like Ribonuclease NYN domain and Ribonuclease Zc3h12a-like, NYN domain.

ztf-16

Caenorhabditis elegans

Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in gonad development and positive regulation of gene expression. Located in nucleus. Expressed in accessory cell; gonad; hypodermis; and tail. Human ortholog(s) of this gene implicated in several diseases, including B-lymphoblastic leukemia/lymphoma; carcinoma (multiple); and common variable immunodeficiency 13. Is an ortholog of several human genes including IKZF1 (IKAROS family zinc finger 1); IKZF2 (IKAROS family zinc finger 2); and IKZF3 (IKAROS family zinc finger 3).

anr-8

Caenorhabditis elegans

Enriched in AFD and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and unc-30 based on RNA-seq studies. Is affected by Doxycycline and paraquat based on RNA-seq studies.

C36A4.12

Caenorhabditis elegans

Enriched in RIM based on single-cell RNA-seq studies. Is affected by several genes including daf-16; smg-2; and etr-1 based on RNA-seq studies. Is affected by Psoralens; allantoin; and Rifampin based on RNA-seq studies.

F46B3.22

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and clk-1 based on RNA-seq and microarray studies. Is affected by four chemicals including multi-walled carbon nanotube; Atrazine; and Colistin based on RNA-seq and microarray studies.

F48C1.11

Caenorhabditis elegans

Is affected by several genes including daf-16; skn-1; and dpy-10 based on microarray and RNA-seq studies. Is affected by twelve chemicals including tryptophan; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies.

K09D9.9

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; multi-walled carbon nanotube; and sucrose based on microarray and RNA-seq studies.

linc-46

Caenorhabditis elegans

Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq studies. Is affected by six chemicals including Tunicamycin; Alovudine; and stavudine based on RNA-seq studies.

nspa-3

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Rifampin; and allantoin based on RNA-seq and microarray studies.

Y24F12A.4

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including hydrogen sulfide; rotenone; and Psoralens based on microarray and RNA-seq studies.

Y41E3.21

Caenorhabditis elegans

Enriched in DA neuron; VA neuron; and neurons based on microarray studies. Is affected by daf-16; etr-1; and tdp-1 based on RNA-seq and microarray studies. Is affected by silicon dioxide nanoparticle based on RNA-seq studies.

Y43D4A.8

Caenorhabditis elegans

Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and hlh-26 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.

Y51H4A.22

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and age-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twelve chemicals including methylmercuric chloride; Tunicamycin; and metformin based on microarray and RNA-seq studies.

C08B6.6

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including methylmercuric chloride; Tunicamycin; and Rifampin based on microarray and RNA-seq studies.

dct-7

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by nineteen chemicals including methylmercuric chloride; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies.

F09F3.8

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by twelve chemicals including multi-walled carbon nanotube; D-glucose; and Psoralens based on RNA-seq and microarray studies.

F14H8.4

Caenorhabditis elegans

Enriched in NSM; XXXL; and XXXR based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and daf-18 based on tiling array; RNA-seq; and microarray studies.

F17E9.2

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty chemicals including aldicarb; methylmercuric chloride; and Tunicamycin based on microarray and RNA-seq studies.

F18A11.6

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; glp-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by Rifampin; Psoralens; and Sirolimus based on RNA-seq studies.

K01D12.10

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by five chemicals including methylmercuric chloride; sucrose; and stearic acid based on microarray and RNA-seq studies.

linc-61

Caenorhabditis elegans

Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on RNA-seq studies. Is affected by silicon dioxide nanoparticle and cadmium based on microarray and RNA-seq studies.

Y38C1AB.3

Caenorhabditis elegans

Is affected by several genes including daf-16; clk-1; and isp-1 based on tiling array; RNA-seq; microarray; and proteomic studies. Is affected by four chemicals including Rifampin; atracurium; and resveratrol based on RNA-seq and microarray studies.

Y41E3.5

Caenorhabditis elegans

Enriched in ADF; ASI; ASJ; head mesodermal cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on microarray and RNA-seq studies.

asp-11

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Tunicamycin; and D-glucose based on microarray and RNA-seq studies.

C01G12.12

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; clk-1; and unc-30 based on RNA-seq and microarray studies. Is affected by allantoin; Sirolimus; and Rifampin based on RNA-seq studies.

C06A1.7

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on tiling array; RNA-seq; and microarray studies. Is affected by silicon dioxide nanoparticle and adsorbable organic bromine compound based on RNA-seq and microarray studies.

C52D10.10

Caenorhabditis elegans

Is affected by several genes including daf-16; dpy-10; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including multi-walled carbon nanotube; Quercetin; and Humic Substances based on RNA-seq and microarray studies.

C54C8.8

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and clk-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; metformin; and Sirolimus based on RNA-seq and microarray studies.

F52G3.6

Caenorhabditis elegans

Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by paraquat based on RNA-seq studies.

H02F09.2

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Cadmium Chloride; Ag nanoparticles; and Cry5B based on RNA-seq and microarray studies.

linc-63

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; cep-1; and mut-16 based on RNA-seq and microarray studies. Is affected by Doxycycline and Tamoxifen based on RNA-seq studies.

nspa-1

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; methylmercuric chloride; and D-glucose based on microarray and RNA-seq studies.

W08F4.3

Caenorhabditis elegans

Predicted to be located in endoplasmic reticulum. Expressed in tail. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 16 and distal spinal muscular atrophy 2. Is an ortholog of human SIGMAR1 (sigma non-opioid intracellular receptor 1).

Y37A1B.18

Caenorhabditis elegans

Is affected by several genes including daf-16; dpy-10; and eat-2 based on RNA-seq and microarray studies. Is affected by twelve chemicals including multi-walled carbon nanotube; Quercetin; and Humic Substances based on RNA-seq and microarray studies.

Y52B11A.14

Caenorhabditis elegans

Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and hsf-1 based on RNA-seq studies. Is affected by metformin; Sirolimus; and Rifampin based on RNA-seq studies.

Y61A9LA.4

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-18 based on microarray and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies.

Y73B3A.11

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by silicon dioxide nanoparticle based on RNA-seq studies.

ZK899.5

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by nine chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq and microarray studies.

AC8.5

Caenorhabditis elegans

Is affected by several genes including daf-16; dpy-21; and cyc-1 based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Atrazine; and cadmium based on RNA-seq and microarray studies.

C11E4.7

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including methylmercuric chloride; manganese chloride; and D-glucose based on microarray and RNA-seq studies.

F42A6.3

Caenorhabditis elegans

Enriched in germ line based on proteomic studies. Is affected by several genes including daf-16; hsf-1; and sir-2.1 based on RNA-seq and microarray studies. Is affected by cadmium and Atrazine based on RNA-seq and microarray studies.

F52B11.8

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Cholestanol; and estrogen based on RNA-seq and microarray studies.

Y71A12B.2

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies.

ZK678.3

Caenorhabditis elegans

Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies.

kin-16

Caenorhabditis elegans

Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in hyp6 and hyp7 syncytium.

C10C6.9

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq studies. Is affected by five chemicals including manganese chloride; stavudine; and Rifampin based on RNA-seq studies.

F09G8.10

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies.

F27D4.3

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq studies.

F46F5.15

Caenorhabditis elegans

Enriched in pm8 based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray; tiling array; and RNA-seq studies. Is affected by methylmercuric chloride and Colistin based on microarray studies.

K08F11.6

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by paraquat and Hydrolyzable Tannins based on RNA-seq and microarray studies.

R07C12.3

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by Alovudine; Testosterone; and dafa#1 based on RNA-seq and microarray studies.

T26H5.11

Caenorhabditis elegans

Enriched in intestine based on RNA-seq studies. Is affected by spt-16; hpx-2; and csr-1 based on RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Rifampin; and Psoralens based on RNA-seq and microarray studies.

C04E12.10

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-12; and lin-4 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; stavudine; and Psoralens based on RNA-seq and microarray studies.

C25H3.18

Caenorhabditis elegans

Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and atfs-1 based on RNA-seq studies. Is affected by four chemicals including rotenone; stavudine; and Rifampin based on RNA-seq studies.

H04D03.6

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and rrf-3 based on RNA-seq studies. Is affected by four chemicals including stavudine; Rifampin; and allantoin based on RNA-seq studies.

pct-1

Caenorhabditis elegans

Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in regulation of transcription involved in G1/S transition of mitotic cell cycle. Located in axon and dendrite. Is an ortholog of human CDK16 (cyclin dependent kinase 16).

T23E1.3

Caenorhabditis elegans

Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by D-glucose; paraquat; and Colistin based on RNA-seq and microarray studies.

W02F12.1

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and unc-30 based on RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

W04G5.12

Caenorhabditis elegans

Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and dpy-21 based on RNA-seq studies. Is affected by five chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies.

W04G5.13

Caenorhabditis elegans

Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq studies. Is affected by five chemicals including metformin; Psoralens; and allantoin based on RNA-seq studies.

Y46H3D.1

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by eleven chemicals including methylmercuric chloride; multi-walled carbon nanotube; and D-glucose based on microarray and RNA-seq studies.

ZC15.4

Caenorhabditis elegans

Enriched in AVK and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on RNA-seq studies. Is affected by Alovudine and resveratrol based on RNA-seq and microarray studies.

D2096.13

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including rotenone; multi-walled carbon nanotube; and Zidovudine based on RNA-seq and microarray studies.

linc-29

Caenorhabditis elegans

Enriched in germ line and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by Alovudine and paraquat based on RNA-seq studies.

nspg-3

Caenorhabditis elegans

Enriched in intestine based on tiling array studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Rifampin; Sirolimus; and allantoin based on RNA-seq studies.

ZK742.4

Caenorhabditis elegans

Predicted to enable FMN binding activity and oxidoreductase activity.

Y59H11AR.6

Caenorhabditis elegans

Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; glp-1; and rrf-3 based on RNA-seq studies. Is affected by eight chemicals including rotenone; Psoralens; and allantoin based on RNA-seq studies.

Y67D8A.10

Caenorhabditis elegans

Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and atfs-1 based on RNA-seq studies. Is affected by Zidovudine and paraquat based on RNA-seq studies.

ZK896.3

Caenorhabditis elegans

Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and glp-1 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq studies.

chil-28

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies.

K01A2.6

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Alovudine; and adsorbable organic bromine compound based on RNA-seq and microarray studies.

K08B12.4

Caenorhabditis elegans

Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; let-418; and chd-3 based on RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq studies.

str-147

Caenorhabditis elegans

Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and rrf-3 based on RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and Rifampin based on RNA-seq studies.

T23F4.1

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by five chemicals including multi-walled carbon nanotube; Humic Substances; and dafa#1 based on RNA-seq and microarray studies.

Y46E12A.5

Caenorhabditis elegans

Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq studies.

Y47D7A.7

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including methylmercury hydroxide; multi-walled carbon nanotube; and D-glucose based on RNA-seq and microarray studies.

Y48A6C.2

Caenorhabditis elegans

Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on RNA-seq and microarray studies. Is affected by Sirolimus and Doxycycline based on RNA-seq and microarray studies.

Y50E8A.14

Caenorhabditis elegans

Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray studies. Is affected by four chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq and microarray studies.

Y53G8AL.3

Caenorhabditis elegans

Enriched in neurons based on tiling array and RNA-seq studies. Is affected by several genes including daf-16; daf-12; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by Atrazine and Sirolimus based on microarray studies.

Y74C9A.6

Caenorhabditis elegans

Enriched in germ line and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and cep-1 based on RNA-seq studies. Is affected by rotenone and atracurium based on RNA-seq studies.

eak-3

Caenorhabditis elegans

Expressed in XXXL and XXXR.

zhp-3

Caenorhabditis elegans

Predicted to enable SUMO transferase activity. Involved in embryo development; meiotic chromosome segregation; and synaptonemal complex disassembly. Located in synaptonemal complex. Is an ortholog of human RNF212B (ring finger protein 212B).

AC8.12

Caenorhabditis elegans

Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.

AC8.7

Caenorhabditis elegans

Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and clk-1 based on microarray and RNA-seq studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.

nspc-5

Caenorhabditis elegans

Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by mianserin and triclosan based on RNA-seq and microarray studies.

pals-36

Caenorhabditis elegans

Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies.

Y50E8A.8

Caenorhabditis elegans

Enriched in male-specific anatomical entity based on microarray studies. Is affected by daf-16; dpy-7; and eat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.

K06B9.2

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and hsf-1 based on microarray and RNA-seq studies. Is affected by four chemicals including allantoin; Sirolimus; and Rifampin based on RNA-seq studies.

nspc-8

Caenorhabditis elegans

Enriched in neurons based on microarray studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including fluvastatin; Deoxyglucose; and Humic Substances based on RNA-seq and microarray studies.

srpr-2.1

Caenorhabditis elegans

Enriched in germ line and sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and pgl-1 based on RNA-seq and microarray studies. Is affected by manganese chloride and paraquat based on RNA-seq studies.

atg-16.2

Caenorhabditis elegans

Involved in defense response to Gram-positive bacterium; gamete generation; and macroautophagy. Located in cytoplasm. Expressed in body wall musculature; embryonic cell; intestine; neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Is an ortholog of human ATG16L1 (autophagy related 16 like 1) and ATG16L2 (autophagy related 16 like 2).

AC8.10

Caenorhabditis elegans

Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and pgl-1 based on RNA-seq studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies.

C45B11.7

Caenorhabditis elegans

Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and rrf-3 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

D1054.19

Caenorhabditis elegans

Enriched in hypodermis and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including daf-16; daf-12; and eat-2 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.

F09E10.10

Caenorhabditis elegans

Is affected by several genes including daf-16; daf-2; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; silicon dioxide nanoparticle; and Colistin based on RNA-seq and microarray studies.

F39E9.10

Caenorhabditis elegans

Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by eight chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq studies.

F47F2.3

Caenorhabditis elegans

Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and daf-12 based on microarray and RNA-seq studies. Is affected by nine chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies.

K09C8.9

Caenorhabditis elegans

Enriched in g1 and neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on RNA-seq and microarray studies. Is affected by 1-methylnicotinamide; cholesterol; and Doxycycline based on RNA-seq studies.

R10E8.7

Caenorhabditis elegans

Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; elt-2; and sir-2.1 based on microarray and RNA-seq studies. Is affected by ten chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq and microarray studies.

T23E1.2

Caenorhabditis elegans

Enriched in germline precursor cell based on RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; mianserin; and stavudine based on RNA-seq studies.

Y61A9LA.5

Caenorhabditis elegans

Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Alovudine; Rifampin; and allantoin based on RNA-seq studies.

AC8.3

Caenorhabditis elegans

Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-16; skn-1; and eat-2 based on RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq and microarray studies.

B0250.12

Caenorhabditis elegans

Enriched in sensory neurons based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and clk-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq studies.

C37C3.10

Caenorhabditis elegans

Enriched in intestine based on tiling array studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on microarray and RNA-seq studies. Is affected by eighteen chemicals including tryptophan; Tunicamycin; and mianserin based on microarray and RNA-seq studies.

F53F4.8

Caenorhabditis elegans

Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and age-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including stavudine; allantoin; and Sirolimus based on RNA-seq and microarray studies.

nspc-6

Caenorhabditis elegans

Enriched in neurons based on microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on RNA-seq and microarray studies. Is affected by ten chemicals including Ethanol; mianserin; and Psoralens based on RNA-seq and microarray studies.

Y39B6A.49

Caenorhabditis elegans

Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and hsp-6 based on RNA-seq studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq and microarray studies.