Predicted to enable misfolded protein binding activity and protein-folding chaperone binding activity. Acts upstream of or within PERK-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum. Expressed in head and tail. Is an ortholog of human DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3).
Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of prefoldin complex. Is an ortholog of human PFDN4 (prefoldin subunit 4).
Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Is an ortholog of human DCAF4 (DDB1 and CUL4 associated factor 4); DCAF4L1 (DDB1 and CUL4 associated factor 4 like 1); and DCAF4L2 (DDB1 and CUL4 associated factor 4 like 2).
Involved in determination of adult lifespan and methylglyoxal metabolic process. Expressed widely. Is an ortholog of human GLOD4 (glyoxalase domain containing 4).