Contributes to ubiquitin-protein transferase activity. Involved in protein ubiquitination and regulation of protein localization to cell surface. Part of ubiquitin conjugating enzyme complex. Expressed in several structures, including intestinal cell. Is an ortholog of human UBE2N (ubiquitin conjugating enzyme E2 N) and UBE2NL (ubiquitin conjugating enzyme E2 N like (gene/pseudogene)).
Involved in nematode male tail tip morphogenesis and transforming growth factor beta receptor signaling pathway. Located in nucleus. Expressed in hyp7 syncytium; intestine; pharynx; ray; and socket cell.