agt-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables damaged DNA binding activity and transferase activity, transferring alkyl or aryl (other than methyl) groups. Involved in DNA dealkylation involved in DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endocrine gland cancer (multiple); and high grade glioma (multiple). Is an ortholog of human MGMT (O-6-methylguanine-DNA methyltransferase).