- dnj-29 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein transmembrane transporter activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane and post-translational protein targeting to endoplasmic reticulum membrane. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of Sec62/Sec63 complex. Human ortholog(s) of this gene implicated in polycystic liver disease. Is an ortholog of human SEC63 (SEC63 homolog, protein translocation regulator).
- F53H1.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in recycling endosome. Is an ortholog of human DENND6A (DENN domain containing 6A) and DENND6B (DENN domain containing 6B).
- C32D5.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transferase activity and zinc ion binding activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 6A. Is an ortholog of human PEX10 (peroxisomal biogenesis factor 10).
- ndua-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease and nuclear type mitochondrial complex I deficiency 13. Is an ortholog of human NDUFA2 (NADH:ubiquinone oxidoreductase subunit A2).
- mtm-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables phosphatase binding activity. Involved in several processes, including nematode larval development; phosphatidylinositol metabolic process; and pinocytosis. Located in apical plasma membrane and cytosol. Expressed in several structures, including anal depressor muscle; coelomocyte; intestinal cell; preanal ganglion; and tail. Used to study centronuclear myopathy. Is an ortholog of human MTMR6 (myotubularin related protein 6); MTMR7 (myotubularin related protein 7); and MTMR8 (myotubularin related protein 8).
- smp-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Involved in nematode male tail mating organ morphogenesis. Predicted to be located in membrane. Expressed in several structures, including hook; inner labial neurons; pharyngeal cell; ray; and vulval cell. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy. Is an ortholog of several human genes including SEMA6A (semaphorin 6A); SEMA6B (semaphorin 6B); and SEMA6C (semaphorin 6C).
- Lce6a [Search on AGR]
Rattus norvegicus Orthologous to human LCE6A (late cornified envelope 6A); INTERACTS WITH 2-hydroxypropanoic acid (ortholog); aflatoxin B1 (ortholog); arsane (ortholog).
- Otud6a [Search on AGR]
Rattus norvegicus Predicted to enable cysteine-type deubiquitinase activity. Orthologous to human OTUD6A (OTU deubiquitinase 6A); INTERACTS WITH Cuprizon; benzo[a]pyrene (ortholog); bisphenol A (ortholog).
- Trappc6a [Search on AGR]
Rattus norvegicus Predicted to be located in endoplasmic reticulum. Orthologous to human TRAPPC6A (trafficking protein particle complex subunit 6A); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.