Predicted to enable 3'-5' DNA helicase activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be part of nucleotide-excision repair factor 3 complex; transcription factor TFIIH holo complex; and transcription preinitiation complex. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; photosensitive trichothiodystrophy 2; and xeroderma pigmentosum group B. Is an ortholog of human ERCC3 (ERCC excision repair 3, TFIIH core complex helicase subunit).