Enables netrin receptor binding activity and non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including anatomical structure morphogenesis; axis specification; and establishment of mitotic spindle orientation. Located in contractile fiber and phagocytic cup. Expressed in several structures, including anchor cell; anus; distal tip cell; head neurons; and vulval cell. Used to study Goldenhar syndrome. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; diabetes mellitus (multiple); gastrointestinal system cancer (multiple); and lung non-small cell carcinoma (multiple). Is an ortholog of human FYN (FYN proto-oncogene, Src family tyrosine kinase); SRC (SRC proto-oncogene, non-receptor tyrosine kinase); and YES1 (YES proto-oncogene 1, Src family tyrosine kinase).
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Is an ortholog of C. elegans Y92H12A.2.
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Is an ortholog of C. elegans Y92H12A.2.
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Is an ortholog of C. elegans Y92H12A.2.
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Is an ortholog of C. elegans Y92H12A.2.