unc-27 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables troponin C binding activity. Involved in locomotion and sarcomere organization. Located in sarcomere. Expressed in body wall musculature; non-striated muscle; and rectal muscle. Human ortholog(s) of this gene implicated in several diseases, including arthrogryposis multiplex congenita; distal arthrogryposis type 2B1; and intrinsic cardiomyopathy (multiple). Is an ortholog of human TNNI1 (troponin I1, slow skeletal type); TNNI2 (troponin I2, fast skeletal type); and TNNI3 (troponin I3, cardiac type).