Predicted to enable clathrin binding activity. Involved in embryo development and receptor-mediated endocytosis. Predicted to be located in cytoplasm and membrane. Predicted to be part of clathrin adaptor complex. Is an ortholog of human AP1B1 (adaptor related protein complex 1 subunit beta 1).
Predicted to enable small GTPase binding activity. Involved in protein secretion. Predicted to be located in trans-Golgi network. Is an ortholog of human GGA1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1).
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Predicted to enable phosphatidylinositol binding activity and ubiquitin binding activity. Is an ortholog of C. elegans apt-9. In C. elegans, apt-9 is involved in protein secretion.
Subunit of the APT subcomplex of cleavage and polyadenylation factor; may have a role in 3' end formation of both polyadenylated and non-polyadenylated RNAs; SYC1 has a paralog, YSH1, that arose from the whole genome duplication
Enables clathrin heavy chain binding activity and protein domain specific binding activity. Involved in several processes, including ecdysis, collagen and cuticulin-based cuticle; egg-laying behavior; and positive regulation of growth rate. Located in cell cortex; clathrin-coated pit; and cytoplasmic vesicle. Expressed in several structures, including P5.ppp; amphid sheath cell; anchor cell; oocyte; and vulval cell. Human ortholog(s) of this gene implicated in autistic disorder and spinocerebellar ataxia type 37. Is an ortholog of human DAB1 (DAB adaptor protein 1).