Predicted to enable alanine-tRNA ligase activity and aminoacyl-tRNA editing activity. Predicted to be involved in alanyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 8 and progressive leukoencephalopathy with ovarian failure. Is an ortholog of human AARS2 (alanyl-tRNA synthetase 2, mitochondrial).
Predicted to enable ATP binding activity and alanine-tRNA ligase activity. Predicted to be involved in alanyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Is an ortholog of C. elegans aars-1.
Predicted to enable ATP binding activity and alanine-tRNA ligase activity. Predicted to be involved in alanyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Is an ortholog of C. elegans aars-1.
Predicted to enable ATP binding activity and alanine-tRNA ligase activity. Predicted to be involved in alanyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Is an ortholog of C. elegans aars-1.
Adenylosuccinate synthase; catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008]
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]