Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to be located in cytoplasm and nucleus. Expressed in intestine; pharyngeal muscle cell; seam cell; and vulval muscle.
Enables calmodulin-dependent protein kinase activity; identical protein binding activity; and transmembrane transporter binding activity. Involved in MAPK cascade; medium-term memory; and positive regulation of gene expression. Acts upstream of or within serotonin biosynthetic process. Located in axon cytoplasm. Expressed in several structures, including AWC; copulatory spicule; gonadal sheath cell; oocyte; and somatic nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; intellectual disability (multiple); and malignant astrocytoma. Is an ortholog of human CAMK2D (calcium/calmodulin dependent protein kinase II delta).
Enriched in neurons based on RNA-seq studies. Is affected by egl-43 based on RNA-seq studies. Is affected by metformin; Sirolimus; and Rifampin based on RNA-seq studies.
Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including hpl-2; egl-43; and etr-1 based on tiling array and RNA-seq studies.