Enables PTB domain binding activity; SH2 domain binding activity; and protein kinase binding activity. Involved in several processes, including dauer exit; regulation of developmental process; and regulation of macromolecule metabolic process. Acts upstream of with a negative effect on protein import into nucleus. Located in several cellular components, including cytoplasmic vesicle; neuronal cell body; and plasma membrane bounded cell projection. Expressed in several structures, including XXX cell; gonad; nerve ring; neurons; and vulva. Used to study Parkinson's disease and diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; glucose metabolism disease (multiple); kidney cancer (multiple); and liver disease (multiple). Is an ortholog of human IGF1R (insulin like growth factor 1 receptor); INSR (insulin receptor); and INSRR (insulin receptor related receptor).