- ins-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables insulin receptor binding activity. Involved in several processes, including insulin receptor signaling pathway; negative regulation of dauer entry; and olfactory learning. Predicted to be located in extracellular space. Expressed in several structures, including ciliated neurons; coelomocyte; head muscle; somatic nervous system; and tail.
- ant-1.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable adenine nucleotide transmembrane transporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. Expressed in VA11 and intestine. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A5 (solute carrier family 25 member 5) and SLC25A6 (solute carrier family 25 member 6).
- pes-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTPase activator activity; actin filament binding activity; and calmodulin binding activity. Predicted to be involved in mitotic actomyosin contractile ring assembly actin filament organization. Predicted to be located in cell cortex. Expressed in ganglia; intestine; muscle cell; and tail. Is an ortholog of human IQGAP1 (IQ motif containing GTPase activating protein 1); IQGAP2 (IQ motif containing GTPase activating protein 2); and IQGAP3 (IQ motif containing GTPase activating protein 3).